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Risk Factors for Low Bone Mineral Density in InstitutionalizedIndividuals with Developmental Disabilities

机译:制度化骨密度低的危险因素发育障碍者

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摘要

>Background: Persons with intellectual/developmental disabilities (IDD) are exposed to several factors, which have been determined as risks for osteoporosis. Many of these individuals are non-ambulatory, resulting in lack of weight bearing activity, which is well established as a major contributor to bone loss. The purpose of this study was to investigate risk factors for low bone mineral density (BMD) in persons with IDD residing in residential facilities. >Methods: This cross-sectional study was conducted at an Intermediate Care Facility for individuals with Intellectual and Developmental Disabilities (ICF/IDD). Medical records data were used from 69 individuals, including heal scan T-scores, nutritional, pharmacologic and other risk factors. Chi-Square analysis was used to determine relationships between the variables. >Results: BMD measures were not significantly associated with age, gender, height, weight, or BMI for this population (P > 0.05). The association between BMD diagnoses and DSM-IV classification of mental retardation approached significance (P = 0.063). A significant association was found with anti-seizure medication (P = 0.009). >Conclusion: Follow-up studies should focus on how supplementation and medication changes may or may not alter BMD. Persons with IDD are experiencing longer life expectancies, and therefore, studies ascertaining information on diseases associated with this aging population are warranted.
机译:>背景:智力/发育障碍(IDD)人士面临多种因素,这些因素被确定为骨质疏松症的风险。这些人中有许多是非卧床的,导致缺乏负重活动,这已被公认是造成骨质流失的主要因素。这项研究的目的是调查居住在住宅设施中的IDD患者低骨密度(BMD)的危险因素。 >方法:该横断面研究是在智障和发育障碍(ICF / IDD)的中级护理机构进行的。使用了69位患者的病历数据,包括健康检查T分数,营养,药理学和其他危险因素。卡方分析用于确定变量之间的关系。 >结果:该人群的BMD测量值与年龄,性别,身高,体重或BMI无关(P> 0.05)。 BMD诊断与智力低下的DSM-IV分类之间的关联具有显着性(P = 0.063)。发现与抗癫痫药物有显着相关性(P = 0.009)。 >结论:后续研究应关注补充剂和药物变化如何改变或不改变BMD。患有IDD的人的预期寿命更长,因此,有必要进行研究以查明与该老龄化人口有关的疾病的信息。

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