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A Pilot Study to Determine the Effect of an Educational DVD in Philippine Languages on Cancer Clinical Trial Participation among Filipinos in Hawai‘i

机译:确定菲律宾语教育DVD对夏威夷菲律宾人癌症临床试验参与的影响的初步研究

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摘要

We conducted an experimental pilot study in an oncology clinic in Honolulu, Hawai‘i to determine the effect of a culturally-tailored educational DVD on cancer clinical trial participation among Filipino cancer patients. Thirty-seven patients participated in the study, with 17 randomized into the control group (ie, usual education) and 20 into the intervention group (ie, usual education plus educational DVD). Participants completed pre- and post-educational questionnaires with items asking about understanding of several cancer topics, behavioral outcomes, and attitudes regarding several treatment and physician related topics. A Fisher's exact test was conducted to explore the association between enrollment into a clinical trial and group assignment. General linear models were created to determine significant differences between study groups in post-education response scores for each questionnaire item after controlling for age, gender, education, and pre-education response scores. Two participants from the control group and three participants from the intervention group enrolled into clinical trials. Results showed no significant association between clinical trial enrollment and study group assignment (P > .99). A significant difference was found between study groups on surety of joining the clinical trial suggested to them (P = .013). A multilingual educational DVD to supplement clinical trial education may positively influence Filipino cancer patients to move forward with the decision to join a cancer clinical trial. However, health literacy may serve as a major barrier to actual enrollment into the particular clinical trial available to a patient.
机译:我们在夏威夷檀香山的一家肿瘤诊所进行了一项实验性试验研究,以确定文化定制的教育DVD对菲律宾癌症患者参与癌症临床试验的影响。 37名患者参加了研究,其中17名随机分为对照组(即常识教育),而20名随机分为干预组(即常识教育和DVD光盘)。参加者完成了教育前后的问卷调查,询问有关对多个癌症主题的理解,行为结果以及对与治疗和医师相关主题的态度的问题。进行了Fisher精确测试,以探索临床试验入组与小组分配之间的关系。在控制了年龄,性别,教育程度和教育前反应分数之后,创建了通用线性模型来确定研究组之间每个问卷项目的教育后反应分数之间的显着差异。对照组的两名参与者和干预组的三名参与者参加了临床试验。结果显示临床试验入组与研究组分配之间无显着关联(P> .99)。研究组之间在建议加入他们的临床试验的确定性上发现了显着差异(P = .013)。补充临床试验教育的多语言教育DVD可能会对菲律宾癌症患者产生积极影响,促使他们决定加入癌症临床试验。但是,健康素养可能成为实际注册患者可用的特定临床试验的主要障碍。

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