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首页> 美国卫生研究院文献>Fungal Biology and Biotechnology >Current challenges of research on filamentous fungi in relation to human welfare and a sustainable bio-economy: a white paper
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Current challenges of research on filamentous fungi in relation to human welfare and a sustainable bio-economy: a white paper

机译：有关人类福利和可持续生物经济的丝状真菌研究的当前挑战：白皮书

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The EUROFUNG network is a virtual centre of multidisciplinary expertise in the field of fungal biotechnology. The first academic-industry Think Tank was hosted by EUROFUNG to summarise the state of the art and future challenges in fungal biology and biotechnology in the coming decade. Currently, fungal cell factories are important for bulk manufacturing of organic acids, proteins, enzymes, secondary metabolites and active pharmaceutical ingredients in white and red biotechnology. In contrast, fungal pathogens of humans kill more people than malaria or tuberculosis. Fungi are significantly impacting on global food security, damaging global crop production, causing disease in domesticated animals, and spoiling an estimated 10 % of harvested crops. A number of challenges now need to be addressed to improve our strategies to control fungal pathogenicity and to optimise the use of fungi as sources for novel compounds and as cell factories for large scale manufacture of bio-based products. This white paper reports on the discussions of the Think Tank meeting and the suggestions made for moving fungal bio(techno)logy forward.
机译：EUROFUNG网络是真菌生物技术领域内多学科专业知识的虚拟中心。 EUROFUNG主持了首个学术界的智囊团，总结了真菌生物学和生物技术的最新发展以及未来十年的挑战。当前，真菌细胞工厂对于白色和红色生物技术中有机酸，蛋白质，酶，次生代谢产物和活性药物成分的批量生产非常重要。相比之下，人类的真菌病原体杀死的人比疟疾或肺结核要多。真菌正在严重影响全球粮食安全，破坏全球农作物产量，在驯养动物中引起疾病​​并破坏估计收成作物的10％。现在需要解决许多挑战，以改善我们控制真菌致病性的策略，并优化真菌作为新型化合物的来源以及大规模生产生物基产品的细胞工厂的使用。本白皮书报告了智库会议的讨论情况以及对推动真菌生物（技术）学发展的建议。

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