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The comparison of predictive performance in bispectral index prediction during target effect-site controlled infusion of propofol using different blood effect-site equilibration rate constants in the same pharmacokinetic model

机译：在相同药代动力学模型中使用不同血液作用部位平衡速率常数的靶点作用部位控释丙泊酚输注期间双光谱指数预测的预测性能比较

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摘要

BackgroundBlood-brain equilibration rate constant (ke0) is derived from either pharmacokinetic and pharmacodynamic modeling (ke0_model) or a model-independent observed time to peak effect (ke0_tpeak). Performance in bispectral index (BIS) prediction was compared between ke0_model and ke0_tpeak for microemulsion or long chain triglyceride (LCT) propofol.

机译：背景血脑平衡速率常数（ke0）从药代动力学和药效学模型（ke0_model）或与模型无关的观察到的达到峰值的时间（ke0_tpeak）得出。对于微乳液或长链甘油三酸酯（LCT）异丙酚，比较了ke0_model和ke0_tpeak的双光谱指数（BIS）预测性能。

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期刊名称 Korean Journal of Anesthesiology
作者
Byung-Moon Choi; Ji-Youn Bang; Kyeo-Woon Jung; Ju-Hyun Lee; Heon-Yong Bae; Gyu-Jeong Noh;
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作者单位

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年(卷),期 2013(65),4
年度 2013
页码 299–305
总页数 7
原文格式 PDF
正文语种
中图分类麻醉学;麻醉学;
关键词
Bispectral index Pharmacokinetic Propofol;

机译：双光谱指数;药代动力学;异丙酚;

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专利

1. The influence of target concentration, equilibration rate constant (k(e0)) and pharmacokinetic model on the initial propofol dose delivered in effect-site target-controlled infusion [J] . Glen J. B., Engbers F. H. M. Anaesthesia: Journal of the Association of Anaesthetists of Great Britain and Ireland . 2016,第3期

机译：目标浓度，平衡速率常数（k（e0））和药代动力学模型对效应位点靶控输注中初始丙泊酚剂量的影响
2. Induction of general anaesthesia by effect-site target-controlled infusion of propofol: Influence of pharmacokinetic model and ke0 value [J] . ThomsonA.J., MorrisonG., ThomsonE., Anaesthesia: Journal of the Association of Anaesthetists of Great Britain and Ireland . 2014,第5期

机译：异丙酚作用部位靶点控制输注诱导全身麻醉：药代动力学模型和ke0值的影响
3. A comparison of the predictive performance of three pharmacokinetic models for propofol using measured values obtained during target-controlled infusion [J] . GlenJ.B., WhiteM. Anaesthesia: Journal of the Association of Anaesthetists of Great Britain and Ireland . 2014,第6期

机译：使用靶控输注过程中获得的测量值比较三种药代动力学模型对异丙酚的预测性能
4. Bispectral index and hemodynamic effects of a constant rate infusion of propofol combined with fentanyl in calves under spontaneous ventilation [C] . M. Deschk, T.A. Trein, J.T. Wagatsuma, Annual Conference of the American^Association^of^Bovine^Practitioners., Conference . 2014

机译：海豚恒定率输注的双光谱指数和血流动力学效应自发通风下犊牛烯基结合芬太尼
5. Performance based tuning strategies for model predictive controllers. [D] . Shridhar, Rahul. 1998

机译：用于模型预测控制器的基于性能的调整策略。
6. Confounding Factors to Predict the Awakening Effect-Site Concentration of Propofol in Target-Controlled Infusion Based on Propofol and Fentanyl Anesthesia [O] . Shun-Ming Chan, Meei-Shyuan Lee, Chueng-He Lu, -1

机译：基于异丙酚和芬太尼麻醉的靶控输注中丙泊酚觉醒作用的现场浓度预测因素
7. The influence of target concentration, equilibration rate constant (ke0) and pharmacokinetic model on the initial propofol dose delivered in effect-site target-controlled infusion [O] . J. B. Glen, F. H. M. Engbers 2015

机译：靶浓度，平衡率常数（KE0）和药代动力学模型对效应 - 位点靶控制输注初始丙糊体剂量的影响
8. Comparison of Proximal Tibia, Proximal Humerus and Distal Femur Infusion Rates of Blood Under High Pressure Using the EX IO Intraosseous Device in the Adult Swine (Sus scrofa) Hypovolemic Model. [R] . Lairet, J., Bebarta, V. 2012

机译：使用成人猪（sus scrofa）低血容量模型中的EX IO骨内装置比较高压下胫骨近端，肱骨近端和远端股骨输注率。

The comparison of predictive performance in bispectral index prediction during target effect-site controlled infusion of propofol using different blood effect-site equilibration rate constants in the same pharmacokinetic model

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