• 主题
高级搜索  >
历史搜索 清空历史
首页> 美国卫生研究院文献>Frontiers in Human Neuroscience >Mental Fatigue and Functional Near-Infrared Spectroscopy (fNIRS) – Based Assessment of Cognitive Performance After Mild Traumatic Brain Injury
【2h】

Mental Fatigue and Functional Near-Infrared Spectroscopy (fNIRS) – Based Assessment of Cognitive Performance After Mild Traumatic Brain Injury

机译：精神疲劳和功能近红外光谱法（fNIRS）–基于轻度颅脑损伤后认知能力的评估

代理获取
本网站仅为用户提供外文OA文献查询和代理获取服务，本网站没有原文。下单后我们将采用程序或人工为您竭诚获取高质量的原文，但由于OA文献来源多样且变更频繁，仍可能出现获取不到、文献不完整或与标题不符等情况，如果获取不到我们将提供退款服务。请知悉。
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Pathological mental fatigue after mild traumatic brain injury (TBI-MF) is characterized by pronounced mental fatigue after cognitive activity. The neurological origin is unknown, and we aimed in the present study to investigate how prolonged mental activity affects cognitive performance and its neural correlates in individuals with TBI-MF. We recruited individuals with TBI-MF (n = 20) at least 5 months after injury, and age-matched healthy controls (n = 20). We used functional near-infrared spectroscopy (fNIRS) to assess hemodynamic changes in the frontal cortex. The self-assessed mental energy level was measured with a visual analog scale (VAS) before and after the experimental procedure. A battery of six neuropsychological tests including Stroop–Simon, Symbol Search, Digit Span, Parallel Serial Mental Operation (PaSMO), Sustained Attention and Working Memory test, and Digit Symbol Coding (DSC) were used. The sequence was repeated once after an 8 min sustained-attention test. The test procedure lasted 2½ h. The experimental procedure resulted in a decrease in mental energy in the TBI-MF group, compared to controls (interaction, p < 0.001, ηp2 = 0.331). The TBI-MF group performed at a similar level on both DSC tests, whereas the controls improved their performance in the second session (interaction, p < 0.01, ηp2 = 0.268). During the Stroop–Simon test, the fNIRS event-related response showed no time effect. However, the TBI-MF group exhibited lower oxygenated hemoglobin (oxy-Hb) concentrations in the frontal polar area (FPA), ventrolateral motor cortex, and dorsolateral prefrontal cortex (DLPFC) from the beginning of the test session. A Stroop and Group interaction was found in the left ventrolateral prefrontal cortex showing that the TBI-MF group did have the same oxy-Hb concentration for both congruent and incongruent trials, whereas the controls had more oxy-Hb in the incongruent trial compared to the congruent trial (interaction, p < 0.01, ηp2 = 0.227). In sum these results indicate that individuals with TBI-MF have a reduced ability to recruit the frontal cortex, which is correlated with self-reported mental fatigue. This may result both in deterioration of cognitive function and the experience of a mental fatigue after extended mental activity.
机译：轻度脑外伤后的病理性精神疲劳（TBI-MF）的特征是认知活动后明显的精神疲劳。神经学的起源是未知的，并且我们在本研究中旨在研究长时间的精神活动如何影响患有TBI-MF的个体的认知能力及其神经相关性。我们招募了受伤后至少5个月患有TBI-MF的个体（n = 20），以及年龄匹配的健康对照组（n = 20）。我们使用功能近红外光谱（fNIRS）评估额叶皮层的血液动力学变化。在实验过程之前和之后，使用视觉模拟量表（VAS）测量自我评估的精神能量水平。使用了六组神经心理学测试，包括Stroop–Simon，符号搜索，数字跨度，并行串行心理操作（PaSMO），持续注意力和工作记忆测试以及数字符号编码（DSC）。经过8分钟的持续注意力测试后，重复该序列一次。测试过程持续2½小时。与对照组相比，该实验程序导致了TBI-MF组的智力下降（交互作用，p <0.001，ηp 2 = 0.331）。 TBI-MF组在两种DSC测试中的表现均相似，而对照组在第二阶段的表现有所提高（相互作用，p <0.01，ηp 2 = 0.268）。在Stroop–Simon测试中，与fNIRS事件相关的反应没有时间效应。然而，从测试开始，TBI-MF组的额叶极区（FPA），腹侧运动皮层和背外侧前额叶皮层（DLPFC）的氧合血红蛋白（oxy-Hb）浓度较低。在左前外侧前额叶皮层中发现Stroop和Group相互作用，这表明TBI-MF组在全同和不一致试验中确实具有相同的oxy-Hb浓度，而对照在非全同试验中的oxy-Hb相比，一致的试验（相互作用，p <0.01，ηp 2 = 0.227）。总之，这些结果表明，患有TBI-MF的人募集额叶皮层的能力降低，这与自我报告的精神疲劳有关。长时间的精神活动可能会导致认知功能下降和精神疲劳。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
代理获取

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号