Systems and Synthetic Biology Approaches to Engineer Fungi for Fine Chemical Production

机译：用于精细化工生产的工程真菌的系统和合成生物学方法

代理获取

本网站仅为用户提供外文OA文献查询和代理获取服务，本网站没有原文。下单后我们将采用程序或人工为您竭诚获取高质量的原文，但由于OA文献来源多样且变更频繁，仍可能出现获取不到、文献不完整或与标题不符等情况，如果获取不到我们将提供退款服务。请知悉。

页面导航

摘要
著录项
相似文献
相关主题

摘要

Since the advent of systems and synthetic biology, many studies have sought to harness microbes as cell factories through genetic and metabolic engineering approaches. Yeast and filamentous fungi have been successfully harnessed to produce fine and high value-added chemical products. In this review, we present some of the most promising advances from recent years in the use of fungi for this purpose, focusing on the manipulation of fungal strains using systems and synthetic biology tools to improve metabolic flow and the flow of secondary metabolites by pathway redesign. We also review the roles of bioinformatics analysis and predictions in synthetic circuits, highlighting in silico systemic approaches to improve the efficiency of synthetic modules.

机译：自系统和合成生物学问世以来，许多研究都试图通过基因和代谢工程方法将微生物作为细胞工厂。酵母和丝状真菌已成功用于生产精细和高附加值的化学产品。在这篇综述中，我们介绍了近年来为此目的使用真菌的一些最有希望的进展，重点是使用系统和合成生物学工具通过途径重新设计改善代谢流和次级代谢产物流的真菌菌株的操作。。我们还将回顾生物信息学分析和预测在合成电路中的作用，重点介绍计算机系统方法，以提高合成模块的效率。

著录项

期刊名称 Frontiers in Bioengineering and Biotechnology
作者
Leonardo Martins-Santana; Luisa C. Nora; Ananda Sanches-Medeiros; Gabriel L. Lovate; Murilo H. A. Cassiano; Rafael Silva-Rocha;
展开▼
作者单位

展开▼
年(卷),期 2018(6),-1
年度 2018
页码 117
总页数 18
原文格式 PDF
正文语种
中图分类生物学;
关键词
synthetic biology yeast filamentous fungi genetic engineering bioinformatics biotechnology;

机译：合成生物学;酵母;丝状真菌;基因工程;生物信息学;生物技术;

相似文献

外文文献
中文文献
专利

1. Systems and synthetic biology approaches to engineer fungi for fine chemical production [J] . Santana Leonardo Martins, Nora Luisa Czamanski, Sanches-Medeiros Ananda, Frontiers in Bioengineering and Biotechnology . 2018,第1期

机译：系统和合成生物学方法来工程化真菌以生产精细化学品
2. Recent Progress on Systems and Synthetic Biology Approaches to Engineer Fungi As Microbial Cell Factories [J] . Gerardo Ruiz Amores, María-Eugenia Guazzaroni, Letícia Magalh?es Arruda, Current genomics . 2016,第2期

机译：工程真菌作为微生物细胞工厂的系统和合成生物学方法的最新进展
3. SYNBIOCHEM Synthetic Biology Research Centre, Manchester – A UK foundry for fine and speciality chemicals production [J] . Le Feuvre RA, Carbonell P, Currin A, Synthetic and Systems Biotechnology . 2016,第4期

机译：曼彻斯特SYNBIOCHEM合成生物学研究中心–英国精细和特种化学品生产铸造厂
4. TOWARDS HIGH-VALUE CHEMICALS PRODUCTION HARNESSING SYNTHETIC BIOLOGY [C] . Eriko Takano Enzyme Engineering Conference . 2018

机译：朝高价值化学品生产利用合成生物学
5. Synthetic and systems biology approaches to characterizing the biochemical events underlying gyrase inhibitor-induced cell death in Escherichia coli. [D] . Dwyer, Daniel John, II. 2007

机译：合成和系统生物学方法来表征大肠杆菌中促旋酶抑制剂诱导的细胞死亡的生化事件。
6. Recent Progress on Systems and Synthetic Biology Approaches to Engineer Fungi As Microbial Cell Factories [O] . Gerardo Ruiz Amores, María-Eugenia Guazzaroni, Letícia Magalhães Arruda, 2016

机译：工程真菌作为微生物细胞工厂的系统和合成生物学方法的最新进展
7. SYNBIOCHEM Synthetic Biology Research Centre, Manchester – A UK foundry for fine and speciality chemicals production [O] . Carbonell, Pablo, Currin, Andrew, Dunstan, Mark, 2016

机译：曼彻斯特SYNBIOCHEM合成生物学研究中心–英国精细和特种化学品生产铸造厂

Systems and Synthetic Biology Approaches to Engineer Fungi for Fine Chemical Production

摘要

著录项

相似文献

相关主题

期刊订阅