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A Systematic Review of 4D-Flow MRI Derived Mitral Regurgitation Quantification Methods

机译:4D流MRI衍生的二尖瓣反流量化方法的系统综述

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摘要

>Background: Four-dimensional flow cardiac magnetic resonance (4D flow CMR) is an emerging non-invasive imaging technology that can be used to quantify mitral regurgitation (MR) volume. Current methods of quantification have demonstrated limitations in accurate analysis, particularly in difficult cases such as complex congenital heart disease. 4D flow CMR methods aim to circumvent these limitations and allow accurate quantification of MR volume even in complex cases. This systematic review aims to summarize the available literature on 4D flow CMR MR quantification methods and examine their ability to accurately classify MR severity.>Methods: Structured searches were carried out on Medline and EMBASE in December 2018 to identify suitable research outcome studies. The titles and abstracts were screened for relevance, with a third adjudicator utilized when study suitability was uncertain.>Results: Seven studies met the eligibility criteria and were included in the systematic review. The most widely used 4D flow MRI method was retrospective valve tracking (RVT) which was examined in five papers. The key finding of these papers was that RVT is a reliable and accurate method of regurgitant volume quantification.>Conclusions: MR quantification through 4D flow MRI is both feasible and accurate. The evidence gathered suggests that for MR assessment, 4D flow MRI is potentially as accurate and reliable to echocardiography and may be complementary to this technique. Further work on MR quantification 4D flow image analysis is needed to determine the most accurate analysis technique and to demonstrate 4D flow MRI as a predictor of clinical outcome.>PROSPERO Registration Number: CRD42019122837,
机译:>背景:二维流心脏磁共振(4D流CMR)是一种新兴的非侵入性成像技术,可用于量化二尖瓣反流(MR)的体积。当前的定量方法已证明在准确分析中存在局限性,特别是在复杂的先天性心脏病等困难病例中。 4D流CMR方法旨在规避这些限制,即使在复杂的情况下也可以对MR体积进行准确定量。本系统综述旨在总结有关4D流CMR MR量化方法的现有文献,并检查其对MR严重性进行准确分类的能力。>方法: 2018年12月在Medline和EMBASE上进行了结构化搜索,以确定合适的方法研究成果研究。筛选标题和摘要的相关性,当不确定研究的适用性时使用第三名评审员。>结果:七项符合条件的研究被纳入系统评价。使用最广泛的4D流MRI方法是回顾性瓣膜追踪(RVT),已在五篇论文中进行了研究。这些论文的主要发现是RVT是一种可靠且准确的反流体积定量方法。>结论:通过4D流MRI进行MR定量既可行又准确。收集的证据表明,对于MR评估,4D流MRI对超声心动图检查可能具有同样的准确性和可靠性,并且可能是这项技术的补充。需要进一步开展MR量化4D流图像分析的工作,以确定最准确的分析技术,并证明4D流MRI可作为临床结果的预测指标。> PROSPERO注册号: CRD42019122837,

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