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Reproductive outcome after IVF following hysteroscopic division of incomplete uterine septum/arcuate uterine anomaly in women with primary infertility

机译：宫腔镜检查不全子宫间隔/弓形子宫异常在宫腔镜检查后IVF后的生殖结局

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Objective: To determine reproductive outcome after in-vitro fertilization/embryo transfer (IVF-ET) in women with primary infertility following hysteroscopic septoplasty of incomplete uterine septum or arcuate uterine anomaly.Methods: This is a historical cohort study. The study group consisted of 156 consecutive patients who underwent a total of 221 cycles of IVF/ET following hysteroscopic septoplasty of an incomplete uterine septum or arcuate anomaly (Group 1). The control group included 196 consecutive patients with normal endometrial cavity on hysteroscopy who underwent a total of 369 cycles of IVF/ET (Group 2). The reproductive outcome after the first cycle of IVF-ET and the best reproductive outcome of all the cycles the patient underwent were calculated. In addition, we compared the reproductive outcome in the study group based on the type of the anomalies (septum versus arcuate).Results: In the first fresh cycle, following septoplasty, there were significantly higher clinical pregnancy and delivery rates in Group 1 (60.3% and 51.3% respectively) compared to Group 2 (38.8% and 33.2% respectively). However, there was no significant difference between the two groups in the clinical pregnancy (74.4% vs. 67.3%) or in the delivery (65.4% vs. 60.2%) rates per patient, respectively. There was no significant difference in the reproductive outcome after IVF-ET between patients who previously had arcuate uterine anomaly versus incomplete uterine septum.Conclusion: Reproductive outcome of IVF-ET after hysteroscopic correction of incomplete uterine septum/arcuate uterine anomaly in women with primary infertility is no different from women with normal uterine cavity.
机译：目的：确定不完全子宫间隔或弓形子宫异常的宫腔镜下子宫成形术后原发不育妇女的体外受精/胚胎移植（IVF-ET）后的生殖结果。方法：这是一项历史性的队列研究。该研究组由156名连续患者组成，他们在宫腔镜下不全子宫间隔或弓形异常行子宫内膜成形术后共进行了221个IVF / ET周期（第1组）。对照组包括196例宫腔镜检查中子宫内膜腔正常的患者，他们总共进行了369个IVF / ET周期（第2组）。计算第一个IVF-ET周期后的生殖结果和患者经历的所有周期中的最佳生殖结果。此外，我们根据异常的类型（隔膜和弓形）比较了研究组的生殖结局。结果：在第一个新鲜周期中，隔隔膜成形后，第1组的临床妊娠和分娩率显着提高（60.3） ％和51.3％）相比，第2组（分别为38.8％和33.2％）。但是，两组的临床妊娠率（74.4％vs. 67.3％）或分娩率（65.4％vs. 60.2％）之间均无显着差异。先前有弓形子宫异常和不完全子宫间隔的患者在IVF-ET后的生殖结局无显着差异。与子宫腔正常的女性没有什么不同。

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