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Gene expression in bryozoan larvae suggest a fundamental importance of pre-patterned blastemic cells in the bryozoan life-cycle

机译:苔藓虫幼虫中的基因表达表明预先形成的胚细胞在苔藓虫生命周期中具有根本的重要性

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摘要

BackgroundBryozoa is a clade of aquatic protostomes. The bryozoan life cycle typically comprises a larval stage, which metamorphoses into a sessile adult that proliferates by asexual budding to form colonies. The homology of bryozoan larvae with other protostome larvae is enigmatic. Bryozoan larvae exhibit blastemic tissues that contribute to build the adult during morphogenesis. However, it remains unclear if the cells of these tissues are pre-determined according to their future fate or if the cells are undifferentiated, pluripotent stem cells. Gene expression studies can help to identify molecular patterning of larval and adult tissues and enlighten the evolution of bryozoan life cycle stages.
机译:背景Bryozoa是一类水生生物。苔藓动物的生命周期通常包括一个幼虫阶段,该幼虫阶段变态为无柄成虫,通过无性芽芽繁殖形成菌落而增殖。苔藓虫幼虫与其他原虫幼虫的同源性是神秘的。苔藓虫幼虫表现出胚芽组织,在形态发生过程中有助于成年。但是,尚不清楚这些组织的细胞是根据它们的未来命运预先确定的,还是这些细胞是未分化的多能干细胞。基因表达研究可以帮助鉴定幼虫和成年组织的分子模式,并启发苔藓动物生命周期阶段的演变。

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