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Stable Angina Medical Therapy Management Guidelines: A Critical Review of Guidelines from the European Society of Cardiology and National Institute for Health and Care Excellence

机译：稳定的心绞痛药物治疗管理指南：欧洲心脏病学会和美国国家卫生与护理研究院卓越指南的严格审查

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Most patients with stable angina can be managed with lifestyle changes, especially smoking cessation and regular exercise, along with taking antianginal drugs. Randomised controlled trials show that antianginal drugs are equally effective and none of them reduced mortality or the risk of MI, yet guidelines prefer the use of beta-blockers and calcium channel blockers as a first-line treatment. The European Society of Cardiology guidelines for the management of stable coronary artery disease provide classes of recommendation with levels of evidence that are well defined. The National Institute for Health and Care Excellence (NICE) guidelines for the management of stable angina provide guidelines based on cost and effectiveness using the terms first-line and second-line therapy. Both guidelines recommend using low-dose aspirin and statins as disease-modifying agents. The aim of this article is to critically appraise the guidelines’ pharmacological recommendations for managing patients with stable angina.
机译：大多数稳定型心绞痛患者可以通过改变生活方式，尤其是戒烟和定期运动，以及服用抗心绞痛药物来治疗。随机对照试验表明，抗心绞痛药物同样有效，但均未降低死亡率或发生MI的风险，但指南更倾向于将β受体阻滞剂和钙通道阻滞剂用作一线治疗药物。欧洲心脏病学会关于稳定冠状动脉疾病管理的指南提供了具有明确定义证据水平的推荐类别。美国国立卫生研究院（National Institute for Health and Care Excellence）（NICE）稳定型心绞痛的治疗指南使用一线和二线治疗术语，基于成本和有效性提供了指南。两项指南均建议使用小剂量阿司匹林和他汀类药物作为缓解疾病的药物。本文的目的是严格评估指南对稳定型心绞痛患者的药理建议。

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