• 主题
高级搜索  >
历史搜索 清空历史
首页> 美国卫生研究院文献>Environmental Health Perspectives >Cytogenetic monitoring in a population occupationally exposed to pesticides in Ecuador.
【2h】

Cytogenetic monitoring in a population occupationally exposed to pesticides in Ecuador.

机译：在厄瓜多尔职业接触农药的人群中进行细胞遗传学监测。

代理获取
本网站仅为用户提供外文OA文献查询和代理获取服务，本网站没有原文。下单后我们将采用程序或人工为您竭诚获取高质量的原文，但由于OA文献来源多样且变更频繁，仍可能出现获取不到、文献不完整或与标题不符等情况，如果获取不到我们将提供退款服务。请知悉。
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

We analyzed the incidence of structural and numerical chromosomal aberrations (CAs) in workers of a plantation of flowers located in Quito, Ecuador, in South America. This study included 41 individuals occupationally exposed to 27 pesticides, some of which are restricted in many countries and are classified as extremely toxic by the World Health Organization; among these are aldicarb and fenamiphos. The same number of individuals of the same age, sex, and geographic area were selected as controls. Workers exposed to these pesticides showed an increased frequency of CA compared with control group (20.59% vs. 2.73%; p < 0.001). We conclude that screening for CA is an adequate biomarker for evaluating and detecting genotoxicity resulting from exposure to pesticides. Levels of erythrocyte acetylcholinesterase were also determined as a complementary metabolic study. Levels below the optimal (> 28 U/mL blood) were found in 88% of exposed individuals; this clearly shows the effect of organophosphate pesticides. When comparing the levels of acetylcholinesterase and structural CA frequencies, there was a negative linear correlation (r = 0.416; p < 0.01). We conclude that by using both analyses it may be possible to estimate damage produced by exposure to organophosphate pesticides.
机译：我们分析了位于南美厄瓜多尔基多的花卉种植园工人的结构和数值染色体畸变（CA）的发生率。这项研究包括41名职业性地暴露于27种农药的人，其中一些在许多国家/地区受到限制，并且被世界卫生组织列为剧毒。其中包括涕灭威和非那磷。选择相同年龄，性别和地理区域的相同数量的个体作为对照。与对照组相比，接触这些农药的工人的CA发生率增加（20.59％比2.73％； p <0.001）。我们得出的结论是，筛查CA是评估和检测由于接触农药引起的遗传毒性的适当生物标记。还确定了红细胞乙酰胆碱酯酶的水平作为补充代谢研究。 88％的暴露个体低于最佳水平（> 28 U / mL血液）；这清楚地表明了有机磷农药的作用。比较乙酰胆碱酯酶水平和结构CA频率时，存在负线性相关性（r = 0.416； p <0.01）。我们得出结论，通过使用这两种分析，可能有可能估算由于接触有机磷酸盐农药而产生的损害。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
代理获取

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号