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Log-binomial models: exploring failed convergence

机译:对数二项式模型:探索失败的收敛

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摘要

BackgroundRelative risk is a summary metric that is commonly used in epidemiological investigations. Increasingly, epidemiologists are using log-binomial models to study the impact of a set of predictor variables on a single binary outcome, as they naturally offer relative risks. However, standard statistical software may report failed convergence when attempting to fit log-binomial models in certain settings. The methods that have been proposed in the literature for dealing with failed convergence use approximate solutions to avoid the issue. This research looks directly at the log-likelihood function for the simplest log-binomial model where failed convergence has been observed, a model with a single linear predictor with three levels. The possible causes of failed convergence are explored and potential solutions are presented for some cases.
机译:背景相对风险是一种流行病学调查中常用的汇总指标。流行病学家越来越多地使用对数二项式模型来研究一组预测变量对单个二进制结果的影响,因为它们自然会带来相对风险。但是,当尝试在特定设置中拟合对数二项式模型时,标准统计软件可能会报告收敛失败。文献中提出的用于解决收敛失败的方法使用了近似解决方案来避免该问题。这项研究直接着眼于最简单的对数二项式模型的对数似然函数,该模型已观察到收敛失败,该模型具有三个级别的单个线性预测变量。探索了收敛失败的可能原因,并针对某些情况提出了潜在的解决方案。

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