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Early Warning System for West Nile Virus Risk Areas California USA

机译:美国加利福尼亚州西尼罗河病毒危险区域预警系统

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摘要

The Dynamic Continuous-Area Space-Time (DYCAST) system is a biologically based spatiotemporal model that uses public reports of dead birds to identify areas at high risk for West Nile virus (WNV) transmission to humans. In 2005, during a statewide epidemic of WNV (880 cases), the California Department of Public Health prospectively implemented DYCAST over 32,517 km2 in California. Daily risk maps were made available online and used by local agencies to target public education campaigns, surveillance, and mosquito control. DYCAST had 80.8% sensitivity and 90.6% specificity for predicting human cases, and κ analysis indicated moderate strength of chance-adjusted agreement for >4 weeks. High-risk grid cells (populations) were identified an average of 37.2 days before onset of human illness; relative risk for disease was >39× higher than for low-risk cells. Although prediction rates declined in subsequent years, results indicate DYCAST was a timely and effective early warning system during the severe 2005 epidemic.
机译:动态连续区域时空(DYCAST)系统是一种基于生物学的时空模型,该模型使用死鸟的公开报告来确定高危险性的西尼罗河病毒(WNV)传播给人类的区域。 2005年,在一次全州WNV流行病(880例)中,加利福尼亚公共卫生部在加利福尼亚州实施了超过32,517 km 2 的DYCAST。每日风险图已在线提供,并由地方机构用于针对公共教育运动,监视和灭蚊的目标。 DYCAST对预测人类病例具有80.8%的敏感性和90.6%的特异性,并且κ分析表明,经过4周以上的机会调整协议的强度中等。在人类疾病发作之前平均37.2天,发现了高风险的网格细胞(种群)。疾病的相对风险比低风险细胞高39倍以上。尽管预测率在随后的几年中有所下降,但结果表明,DYCAST是在2005年严重流行期间及时有效的预警系统。

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