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Mapping microbial ecosystems and spoilage-gene flow in breweries highlights patterns of contamination and resistance

机译:绘制啤酒厂中的微生物生态系统和腐败基因流图彰显了污染和耐药性的模式

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摘要

Distinct microbial ecosystems have evolved to meet the challenges of indoor environments, shaping the microbial communities that interact most with modern human activities. Microbial transmission in food-processing facilities has an enormous impact on the qualities and healthfulness of foods, beneficially or detrimentally interacting with food products. To explore modes of microbial transmission and spoilage-gene frequency in a commercial food-production scenario, we profiled hop-resistance gene frequencies and bacterial and fungal communities in a brewery. We employed a Bayesian approach for predicting routes of contamination, revealing critical control points for microbial management. Physically mapping microbial populations over time illustrates patterns of dispersal and identifies potential contaminant reservoirs within this environment. Habitual exposure to beer is associated with increased abundance of spoilage genes, predicting greater contamination risk. Elucidating the genetic landscapes of indoor environments poses important practical implications for food-production systems and these concepts are translatable to other built environments.>DOI:
机译:独特的微生物生态系统已经演变成能够应对室内环境的挑战,从而形成了与现代人类活动相互作用最密切的微生物群落。食品加工设施中的微生物传播会对食品的质量和健康产生巨大影响,从而有利或有害地与食品相互作用。为了探索商业食品生产场景中微生物传播和腐败基因频率的模式,我们分析了啤酒花中啤酒花抗性基因频率以及细菌和真菌群落。我们采用贝叶斯方法预测污染的途径,揭示了微生物管理的关键控制点。随时间推移对微生物种群的物理分布图说明了扩散模式,并确定了该环境中潜在的污染物库。经常性地暴露于啤酒会增加腐败基因的含量,从而预示着更大的污染风险。阐明室内环境的遗传景观对食品生产系统具有重要的实际意义,这些概念可以转化为其他建筑环境。> DOI:

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