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Negative-pressure wound therapy for management of diabetic foot wounds: a review of the mechanism of action clinical applications and recent developments

机译:负压伤口疗法治疗糖尿病足伤口:作用机理临床应用和最新进展的综述

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摘要

Negative-pressure wound therapy (NPWT) plays an important role in the treatment of complex wounds. Its effect on limb salvage in the management of the diabetic foot is well described in the literature. However, a successful outcome in this subgroup of diabetic patients requires a multidisciplinary approach with careful patient selection, appropriate surgical debridement, targeted antibiotic therapy, and optimization of healing markers. Evolving NPWT technology including instillation therapy, nanocrystalline adjuncts, and portable systems can further improve results if used with correct indications. This review article summarizes current knowledge about the role of NPWT in the management of the diabetic foot and its mode of action, clinical applications, and recent developments.
机译:负压伤口治疗(NPWT)在复杂伤口的治疗中起着重要作用。在糖尿病足的治疗中它对肢体抢救的作用在文献中有很好的描述。但是,要在该糖尿病患者亚组中取得成功的结果,就需要采取多学科的方法,并仔细选择患者,适当的手术清创术,靶向抗生素治疗以及优化治疗指标。如果使用正确的适应症,包括滴注疗法,纳米晶体辅助剂和便携式系统在内的不断发展的NPWT技术可以进一步改善治疗效果。这篇综述文章总结了有关NPWT在糖尿病足管理中的作用及其作用方式,临床应用和最新进展的最新知识。

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