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KDIGO 2017 Clinical Practice Guideline Update for the Diagnosis Evaluation Prevention and Treatment of Chronic Kidney Disease–Mineral and Bone Disorder (CKD-MBD)

机译：KDIGO 2017年临床实践指南更新用于诊断评估预防和治疗慢性肾脏病-矿物质和骨疾病（CKD-MBD）

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The Kidney Disease: Improving Global Outcomes (KDIGO) 2017 Clinical Practice Guideline Update for the Diagnosis, Evaluation, Prevention, and Treatment of chronic kidney disease–mineral and bone disorder (CKD-MBD) represents a selective update of the prior guideline published in 2009. This update, along with the 2009 publication, is intended to assist the practitioner caring for adults and children with CKD, those on chronic dialysis therapy, or individuals with a kidney transplant. Specifically, the topic areas for which updated recommendations are issued include diagnosis of bone abnormalities in CKD-MBD; treatment of CKD-MBD by targeting phosphate lowering and calcium maintenance, treatment of abnormalities in parathyroid hormone in CKD-MBD; treatment of bone abnormalities by antiresorptives and other osteoporosis therapies; and evaluation and treatment of kidney transplant bone disease. Development of this guideline update followed an explicit process of evidence review and appraisal. Treatment approaches and guideline recommendations are based on systematic reviews of relevant trials, and appraisal of the quality of the evidence and the strength of recommendations followed the GRADE (Grading of Recommendations Assessment, Development, and Evaluation) approach. Limitations of the evidence are discussed, with areas of future research also presented.>Keywords: bone abnormalities; bone mineral density; calcium; chronic kidney disease; CKD-MBD; dialysis; guideline; hyperparathyroidism; hyperphosphatemia; KDIGO; kidney transplantation; mineral and bone disorder; parathyroid hormone; phosphate; phosphorus; systematic review>CITATIONIn citing this document, the following format should be used: Kidney Disease: Improving Global Outcomes (KDIGO) CKD-MBD Update Work Group. KDIGO 2017 Clinical Practice Guideline Update for the Diagnosis, Evaluation, Prevention, and Treatment of Chronic Kidney Disease–Mineral and Bone Disorder (CKD-MBD). Kidney Int Suppl. 2017;7:1–59.
机译：肾脏疾病：改善全球结局（KDIGO）2017年临床实践指南更新，用于诊断，评估，预防和治疗慢性肾脏病-矿物质和骨病（CKD-MBD），代表对2009年发布的先前指南的选择性更新此更新与2009年出版物一起，旨在帮助从业者照顾患有CKD的成人和儿童，正在接受慢性透析治疗的人或进行肾脏移植的人。具体而言，发布更新建议的主题区域包括CKD-MBD中骨骼异常的诊断；通过降低磷酸盐和钙的维持来治疗CKD-MBD，治疗CKD-MBD的甲状旁腺激素异常；通过抗吸收剂和其他骨质疏松疗法治疗骨异常；肾移植骨疾病的评估和治疗。本指南更新的制定遵循了明确的证据审查和评估过程。治疗方法和指南建议基于对相关试验的系统评价，并遵循GRADE（建议书评级，评估和评估）方法对证据质量和建议强度进行评估。讨论了证据的局限性，并提出了未来的研究领域。>关键词：骨异常；骨密度;钙;慢性肾病; CKD-MBD;透析指导方针甲状旁腺功能亢进;高磷酸盐血症; KDIGO；肾脏移植；矿物质和骨骼疾病；甲状旁腺激素磷酸盐磷;系统评价>引文在引用本文档时，应使用以下格式：肾脏疾病：改善全球结局（KDIGO）CKD-MBD更新工作组。 KDIGO 2017临床实践指南更新，用于诊断，评估，预防和治疗慢性肾脏病-矿物质和骨病（CKD-MBD）。肾脏国际供应商2017; 7：1–59。

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