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Noninvasive Measurement of Conductivity Anisotropy at Larmor Frequency Using MRI

机译:使用MRI的无创测量电导率各向异性

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摘要

Anisotropic electrical properties can be found in biological tissues such as muscles and nerves. Conductivity tensor is a simplified model to express the effective electrical anisotropic information and depends on the imaging resolution. The determination of the conductivity tensor should be based on Ohm's law. In other words, the measurement of partial information of current density and the electric fields should be made. Since the direct measurements of the electric field and the current density are difficult, we use MRI to measure their partial information such as B1 map; it measures circulating current density and circulating electric field. In this work, the ratio of the two circulating fields, termed circulating admittivity, is proposed as measures of the conductivity anisotropy at Larmor frequency. Given eigenvectors of the conductivity tensor, quantitative measurement of the eigenvalues can be achieved from circulating admittivity for special tissue models. Without eigenvectors, qualitative information of anisotropy still can be acquired from circulating admittivity. The limitation of the circulating admittivity is that at least two components of the magnetic fields should be measured to capture anisotropic information.
机译:在诸如肌肉和神经的生物组织中可以发现各向异性的电特性。电导率张量是简化模型,用于表示有效的各向异性信息,并且取决于成像分辨率。电导率张量的确定应基于欧姆定律。换句话说,应该测量电流密度和电场的部分信息。由于很难直接测量电场和电流密度,因此我们使用MRI来测量它们的局部信息,例如B1图。它测量循环电流密度和循环电场。在这项工作中,提出了两个循环场之比,称为循环导纳率,作为拉莫尔频率下电导率各向异性的量度。给定电导率张量的特征向量,就可以通过特殊组织模型的循环导纳来实现特征值的定量测量。如果没有特征向量,则仍然可以从循环导纳中获取各向异性的定性信息。循环介电常数的局限性在于,应测量磁场的至少两个分量以捕获各向异性信息。

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