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Delay decomposition approach to ... formula ... filtering analysis of genetic oscillator networks with time-varying delays

机译:具有时变时滞的遗传振荡器网络的延迟分解法...

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摘要

In this paper, the ℋ∞ filtering problem is treated for N coupled genetic oscillator networks with time-varying delays and extrinsic molecular noises. Each individual genetic oscillator is a complex dynamical network that represents the genetic oscillations in terms of complicated biological functions with inner or outer couplings denote the biochemical interactions of mRNAs, proteins and other small molecules. Throughout the paper, first, by constructing appropriate delay decomposition dependent Lyapunov–Krasovskii functional combined with reciprocal convex approach, improved delay-dependent sufficient conditions are obtained to ensure the asymptotic stability of the filtering error system with a prescribed ℋ∞ performance. Second, based on the above analysis, the existence of the designed ℋ∞ filters are established in terms of linear matrix inequalities with Kronecker product. Finally, numerical examples including a coupled Goodwin oscillator model are inferred to illustrate the effectiveness and less conservatism of the proposed techniques.
机译:本文针对具有时变时滞和外在分子噪声的N个耦合遗传振荡器网络处理ℋ∞滤波问题。每个单独的遗传振荡器都是一个复杂的动力学网络,代表具有复杂的生物学功能的遗传振荡,具有内部或外部耦合,表示mRNA,蛋白质和其他小分子的生化相互作用。在整篇论文中,首先,通过构造适当的时滞分解相关的Lyapunov–Krasovskii泛函结合倒数凸方法,获得了改进的时延相关的充分条件,以确保具有规定ℋ∞性能的滤波误差系统的渐近稳定性。其次,基于以上分析,根据Kronecker积的线性矩阵不等式建立了设计的the∞滤波器。最后,推导了包括耦合的古德温振荡器模型的数值示例,以说明所提出技术的有效性和较低的保守性。

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