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Linkage disequilibrium pattern of the ATM gene in breast cancer patients and controls; association of SNPs and haplotypes to radio-sensitivity and post-lumpectomy local recurrence

机译：乳腺癌患者和对照中ATM基因的连锁不平衡模式；单核苷酸多态性和单倍型与放射敏感性和肿块切除术后局部复发的关系

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BackgroundThe ATM protein is activated as a result of ionizing radiation, and genetic variants of the ATM gene may therefore affect the level of radiation-induced damage. Individuals heterozygous for ATM mutations have been reported to have an increased risk of malignancy, especially breast cancer.

机译：背景技术ATM蛋白由于电离辐射而被激活，因此ATM基因的遗传变异可能会影响辐射诱导的损伤水平。据报道，ATM突变杂合的个体患恶性肿瘤的风险增加，尤其是乳腺癌。

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期刊名称 Radiation Oncology (London England)
作者
Hege Edvardsen; Toril Tefre; Laila Jansen; Phuong Vu; Bruce G Haffty; Sophie D Fosså; Vessela N Kristensen; Anne-Lise Børresen-Dale;
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年(卷),期 2007(2),-1
年度 2007
页码 25
总页数 9
原文格式 PDF
正文语种
中图分类肿瘤学;放射医学;影像诊断学;
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1. Linkage disequilibrium pattern of the ATM gene in breast cancer patients and controls; association of SNPs and haplotypes to radio-sensitivity and post-lumpectomy local recurrence [J] . Hege Edvardsen, Toril Tefre, Laila Jansen, Radiation oncology . 2007,第1期

机译：乳腺癌患者和对照中ATM基因的连锁不平衡模式;单核苷酸多态性和单倍型与放射敏感性和肿块切除术后局部复发的关系
2. Linkage disequilibrium pattern of the ATM gene in breast cancer patients and controls; association of SNPs and haplotypes to radio-sensitivity and post-lumpectomy local recurrence [J] . Hege Edvardsen, Toril Tefre, Laila Jansen, Radiation oncology . 2007,第1期

机译：乳腺癌患者和对照中ATM基因的连锁不平衡模式;单核苷酸多态性和单倍型与放射敏感性和肿块切除术后局部复发的关系
3. Haplotype patterns in cancer-related genes with long-range linkage disequilibrium: no evidence of association with breast cancer or positive selection. [J] . Ribas G, Milne RL, Gonzalez-Neira A, European journal of human genetics: EJHG . 2008,第2期

机译：具有远距离连锁不平衡的癌症相关基因的单倍型模式：没有证据表明与乳腺癌或阳性选择有关。
4. A TOOL FOR SELECTING SNPS FOR ASSOCIATION STUDIES BASED ON OBSERVED LINKAGE DISEQUILIBRIUM PATTERNS [C] . FRANCISCO M. DE LA VEGA, HADAR I. ISAAC, CHARLES R. SCAFE Pacific Symposium on Biocomputing 2006 . 2006

机译：基于观察到的连锁不平衡模式的用于关联研究的SNPS选择工具
5. Associations between candidate cytokine genes and sleep disturbances among two latent classes of breast cancer patients prior to and following treatment. [D] . Alfaro, Emely. 2012

机译：在治疗前后，两种潜在的乳腺癌患者中候选细胞因子基因与睡眠障碍之间的关联。
6. A complete linkage disequilibrium in a haplotype of three SNPs in Fat Mass and Obesity associated (FTO) gene was strongly associated with anthropometric indices after controlling for calorie intake and physical activity [O] . Naser Kalantari, Nastaran Keshavarz Mohammadi, Pantea Izadi, 2018

机译：控制卡路里的摄入和身体活动后脂肪质量和肥胖相关（FTO）基因中三个SNP的单倍型的完全连锁不平衡与人体测量学指标密切相关
7. Linkage disequilibrium pattern of the ATM gene in breast cancer patients and controls; association of SNPs and haplotypes to radio-sensitivity and post-lumpectomy local recurrence [O] . Edvardsen, Hege, Tefre, Toril, Jansen, Laila, 2007

机译：乳腺癌患者和对照中ATM基因的连锁不平衡模式；单核苷酸多态性和单倍型与放射敏感性和肿块切除术后局部复发的关系

Linkage disequilibrium pattern of the ATM gene in breast cancer patients and controls; association of SNPs and haplotypes to radio-sensitivity and post-lumpectomy local recurrence

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