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Comparative study between peripherally and centrally acting sublethal and lethal doses of Leiurus quinquestriatus scorpion venom in rabbits: The usefulness of the sodium channel blocker lidocaine

机译：体内和体外作用的Leirus quinquestriatus蝎毒的致死和致死剂量之间的比较研究：钠通道阻滞剂利多卡因的有效性

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BackgroundScorpion envenomation is common among desert dwellers, affecting several systems and resulting in multiple organ dysfunction (MOD) or failure (MOF), mainly due to their action on Na⁺ channels. Although scorpion venoms toxins do not pass the blood brain barrier, their CNS effects are prominent, occurring in conjunction with, or as an aftermath of peripheral actions of the venom.

机译：背景蝎毒在沙漠居民中很普遍，会影响多个系统并导致多器官功能障碍（MOD）或功能衰竭（MOF），这主要是由于它们对Na ^{+ 通道的作用。尽管蝎子毒液毒素没有通过血脑屏障，但它们的中枢神经系统作用却很突出，与毒液的周围作用同时发生或作为其后遗症发生。}

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期刊名称 Saudi Pharmaceutical Journal : SPJ
作者
Amal J. Fatani;
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作者单位

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年(卷),期 2010(18),3
年度 2010
页码 137–151
总页数 15
原文格式 PDF
正文语种
中图分类药学;
关键词
Leiurus quinquestriatus Scorpion venom Cardiac output Estimated hepatic blood flow Blood pressure Lidocaine Pulmonary index Histopathological manifestations;

机译：Leinurus quinquestriatus;蝎毒;心输出量;估计的肝血流量;血压;利多卡因;肺指数;组织病理学表现;

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1. Comparative study between peripherally and centrally acting sublethal and lethal doses of Leiurus quinquestriatus scorpion venom in rabbits: The usefulness of the sodium channel blocker lidocaine [J] . Amal J.Fatani Saudi Pharmaceutical Journal . 2010,第3期

机译：体内和体外剂量的Leiurus quinquestriatus蝎毒的致死和致死剂量之间的比较研究：钠通道阻滞剂利多卡因的有效性
2. The effects of a sodium and a calcium channel blocker on lethality of mice injected with the yellow scorpion (Leiurus quinquestriatus) venom [J] . Journal of Venomous Animals and Toxins including Tropical Diseases . 2005,第2期

机译：钠和钙通道阻滞剂对注射黄蝎（Leiurus quinquestriatus）毒液的小鼠的致死率的影响
3. Correlation between blood pressure, cytokines and nitric oxide in conscious rabbits injected with Leiurus quinquestriatus quinquestriatus scorpion venom [J] . Abdoon NA, Fatani AJ Toxicon: An International Journal Devoted to the Exchange of Knowledge on the Poisons Derived from Animals, Plants and Microorganisms . 2009,第4期

机译：注射了Leiurus quinquestriatus quinquestriatus蝎毒的清醒兔子的血压，细胞因子和一氧化氮的相关性
4. Effects of potassium channel toxins from Leiurus quinquestriatus hebraeus venom on responses to cromakalim in rabbit blood vessels. [O] . P. N. Strong, S. W. Weir, D. J. Beech, 1989

机译：西伯利亚Leiurus quinquestriatus蛇毒钾通道毒素对兔血管中对cromakalim反应的影响。
5. Comparative study between peripherally and centrally acting sublethal and lethal doses of Leiurus quinquestriatus scorpion venom in rabbits: The usefulness of the sodium channel blocker lidocaine [O] . Fatani Amal J. 2010

机译：周围和中央作用的致死Leirurus quinquestriatus蝎毒的亚致死剂量的比较研究：钠通道阻滞剂利多卡因的有效性

Comparative study between peripherally and centrally acting sublethal and lethal doses of Leiurus quinquestriatus scorpion venom in rabbits: The usefulness of the sodium channel blocker lidocaine

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