• 主题
高级搜索  >
历史搜索 清空历史
首页> 美国卫生研究院文献>Toxicological Research >Increased Flavonoid Compounds from Fermented Houttuynia cordata using Isolated Six of Bacillus from Traditionally Fermented Houttuynia cordata
【2h】

Increased Flavonoid Compounds from Fermented Houttuynia cordata using Isolated Six of Bacillus from Traditionally Fermented Houttuynia cordata

机译：使用分离自传统发酵鱼腥草的六种芽孢杆菌增加发酵鱼腥草中的黄酮类化合物

代理获取
本网站仅为用户提供外文OA文献查询和代理获取服务，本网站没有原文。下单后我们将采用程序或人工为您竭诚获取高质量的原文，但由于OA文献来源多样且变更频繁，仍可能出现获取不到、文献不完整或与标题不符等情况，如果获取不到我们将提供退款服务。请知悉。
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Flavonoids, which form a major component in Houttuynia cordata Thunb., display a wide range of pharmacological activities. The expression of plant flavonoids is partly regulated by fermentation. Therefore, we studied the effects of fermentation on H. cordata in order to identify the strains present during the fermentation process, and to determine whether fermented H. cordata could be used as a probiotic. Our results showed that all 6 of the bacterial strains isolated from fermented H. cordata (FHC) belonged to the genus Bacillus. As expected, fermenting H cordata also increased the flavonoid content as increases were observed in the levels of rutin, quercitrin, and quercetin. To test the effects of fermentation, we treated LPS-stimulated RAW264.7 cells with non-fermented H. cordata extracts (HCE) or FHC extracts (FHCE). Compared to the HCE-treated cells, the FHCE-treated cells showed increased viability. No cytotoxic effects were detected in the FHCE-treated groups in the 2 cell lines used in the study, namely, RAW264.7 and RBL-2H3. FHCE-treated HepG2 cells showed decreased growth, compared to HCE-treated HepG2 cells. These results indicate that the fermented H. cordata predominantly contained Bacillus strains. Furthermore, FHCE are able to prevent LPS-induced inflammatory effects and inhibit the growth of HepG2 cells.
机译：类黄酮是鱼腥草的主要成分，具有广泛的药理活性。植物类黄酮的表达部分受发酵调节。因此，我们研究了发酵对虫草的影响，以鉴定发酵过程中存在的菌株，并确定发酵的虫草是否可以用作益生菌。我们的研究结果表明，从发酵的脐带血丝菌（FHC）分离出的所有6个细菌菌株均属于芽孢杆菌属。不出所料，发酵的脐带血也增加了类黄酮含量，因为芦丁，槲皮素和槲皮素的含量有所增加。为了测试发酵的效果，我们用未发酵的堇菜提取物（HCE）或FHC提取物（FHCE）处理了LPS刺激的RAW264.7细胞。与HCE处理的细胞相比，FHCE处理的细胞显示出增加的生存力。在研究中使用的2种细胞系RAW264.7和RBL-2H3中，在FHCE处理组中未检测到细胞毒性作用。与HCE处理的HepG2细胞相比，FHCE处理的HepG2细胞显示出生长减少。这些结果表明，发酵的堇青丝菌主要含有芽孢杆菌菌株。此外，FHCE能够预防LPS诱导的炎症作用并抑制HepG2细胞的生长。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
代理获取

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号