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The contemporary role of 1 vs. 2-stage repair for proximal hypospadias

机译:近距离尿道下裂1阶段修复与2阶段修复的当代作用

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摘要

This review discusses the most commonly employed techniques in the repair of proximal hypospadias, highlighting the advantages and disadvantages of single versus staged surgical techniques. Hypospadias can have a spectrum of severity with a urethral meatus ranging from the perineum to the glans. Associated abnormalities are commonly found with proximal hypospadias and encompass a large spectrum, including ventral curvature (VC) up to 50 degrees or more, ventral skin deficiency, a flattened glans, penile torsion and penoscrotal transposition. Our contemporary understanding of hypospadiology is comprised of a foundation built by experts who have described a number of techniques and their outcomes, combined with survey data detailing practice patterns. The two largest components of hypospadias repair include repair of VC and urethroplasty. VC greater than 20 degrees is considered clinically relevant to warrant surgical correction. To repair VC, the penis is first degloved—a procedure that may reduce or remove curvature by itself in some cases. Residual curvature is then repaired with dorsal plication techniques, transection of the urethral plate, and/or ventral lengthening techniques. Urethroplasty takes the form of 1- or 2-stage repairs. One-stage options include the tubularized incised urethroplasty (TIP) or various graft or flap-based techniques. Two-stage options also include grafts or flaps, including oral mucosal and preputial skin grafting. One stage repairs are an attractive option in that they may reduce cost, hospital stay, anesthetic risks, and time to the final result. The downside is that these repairs require mastery of multiple techniques may be more complex, and—depending on technique—have higher complication rates. Two-stage repairs are preferred by the majority of surveyed hypospadiologists. The 2-stage repair is versatile and has satisfactory outcomes, but necessitates a second procedure. Given the lack of clear high-quality evidence supporting the superiority of one approach over the others, hypospadiologists should develop their own algorithm, which gives them the best outcomes.
机译:这篇综述讨论了近端尿道下裂修复中最常用的技术,强调了单阶段手术技术与分期手术技术的优缺点。尿道下裂的严重程度范围从会阴到龟头都有尿道口。伴有近尿道下裂的异常通常见于广泛的范围,包括高达50度或更高的腹侧弯曲(VC),腹侧皮肤缺乏症,龟头扁平,阴茎扭转和阴囊移位。我们当代对尿道下裂的认识是由专家建立的基础,这些专家描述了多种技术及其成果,并结合了详细说明实践模式的调查数据。尿道下裂修复的两个最大组成部分包括VC修复和尿道成形术。 VC大于20度被认为与临床相关,需要手术矫正。为了修复VC,首先将阴茎脱灰-在某些情况下可能会自行减少或消除弯曲。然后用背折技术,尿道板横切术和/或腹侧延长技术修复残余曲率。尿道成形术采用1阶段或2阶段修复的形式。一阶段选择包括管状切开的尿道成形术(TIP)或各种基于移植或皮瓣的技术。两阶段选择还包括移植物或皮瓣,包括口腔粘膜和皮损皮肤移植。一级修复是一种有吸引力的选择,因为它可以减少成本,缩短住院时间,降低麻醉风险并缩短最终结果的时间。不利的一面是,这些维修需要掌握多种技术,可能会更复杂,并且根据技术的不同,其并发症发生率也更高。大多数接受过调查的尿道下裂科医生都倾向于两阶段修复。 2阶段修复功能多样,效果令人满意,但必须进行第二次手术。鉴于缺乏明确的高质量证据来支持一种方法优于另一种方法,因此,尿道下裂学家应开发自己的算法,从而为他们提供最佳结果。

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