Distinctive Effect of Donepezil Treatment on P300 and N200 Subcomponents of Auditory Event-Related Evoked Potentials in Alzheimer Disease Patients

机译：多奈哌齐治疗对阿尔茨海默病患者听觉事件相关诱发电位中P300和N200亚组分的显着影响

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BackgroundLatency of P300 subcomponent of event-related potentials (ERPs) increases in Alzheimer disease (AD) patients, which correlate well with cognitive impairment. Cholinesterase inhibitors (ChEIs) reduce P300 latency in AD patients with parallel improvement in cognition. It is not known whether N200 response to ChEIs is similar to that of P300.The aim of this study was to evaluate and compare characteristics of P300 and N200 in AD patients, treatment-naïve and on stable donepezil treatment, matched by age, education, sex, and cognitive function.

机译：背景阿尔茨海默病（AD）患者的事件相关电位（ERP）P300亚成分的潜伏期增加，这与认知障碍密切相关。胆碱酯酶抑制剂（ChEIs）可降低AD患者的P300潜伏期，同时认知能力也会得到改善。目前尚不清楚N200对ChEIs的反应是否与P300相似。本研究的目的是评估和比较AD患者，未经治疗和稳定的多奈哌齐治疗中P300和N200的特征，并根据年龄，学历，性别和认知功能。

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期刊名称 Medical Science Monitor : International Medical Journal of Experimental and Clinical Research
作者
Arūnas Vaitkevičius; Gintaras Kaubrys; Eglė Audronytė;
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作者单位

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年(卷),期 2015(21),-1
年度 2015
页码 1920–1927
总页数 8
原文格式 PDF
正文语种
中图分类
关键词
Alzheimer Disease Cholinesterase Inhibitors Dementia Event-Related Potentials P300 Neurobehavioral Manifestations Neuropsychological Tests;

机译：阿尔茨海默氏病;胆碱酯酶抑制剂;痴呆;与事件相关的电位;P300;神经行为表现;神经心理学测试;

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1. Distinctive Effect of Donepezil Treatment on P300 and N200 Subcomponents of Auditory Event-Related Evoked Potentials in Alzheimer Disease Patients [J] . Arūnas Vaitkevi?ius, Gintaras Kaubrys, Egl? Audronyt? Medical science monitor : . 2015,第1期

机译：多奈哌齐治疗对阿尔茨海默病患者听觉事件相关诱发电位中P300和N200亚组分的显着影响
2. Diagnostic value of event-related evoked potentials N200 and P300 subcomponents in early diagnosis of Alzheimer's disease and mild cognitive impairment. [J] . Bennys K, Portet F, Touchon J, Journal of Clinical Neurophysiology . 2007,第5期

机译：事件相关诱发电位N200和P300子组件在阿尔茨海默氏病和轻度认知障碍的早期诊断中的诊断价值。
3. The clinical utility of the auditory P300 latency subcomponent event-related potential in preclinical diagnosis of patients with mild cognitive impairment and Alzheimer's disease [J] . Aaron S. Howe, Ali Bani-Fatemi, Vincenzo De Luca Brain and cognition . 2014,第apra期

机译：听觉P300潜伏期亚组分事件相关电位在轻度认知障碍和阿尔茨海默氏病患者临床前诊断中的临床应用
4. Event-related evoked potentials in Alzheimer's disease by a tool-using gesture paradigm [C] . Chan, Hsiao-Lung, Hsu, Wen-Chun, Meng, Ling-Fu, Annual Conference of Japanese Society for Medical and Biological Engineering;Annual International Conference of the IEEE Engineering in Medicine and Biology Society . 2013

机译：使用工具的手势范例在阿尔茨海默氏病中与事件相关的诱发电位
5. Visual event-related evoked potentials using Continuous Performance Task comparing dementia of Alzheimer's type patients and normal aging adults. [D] . Wen, Johnny H. 2003

机译：使用持续表现任务比较阿尔茨海默氏症型患者和正常老年人的痴呆症，可以发现与视觉事件相关的诱发电位。
6. Characterization of N200 and P300: Selected Studies of the Event-Related Potential [O] . Salil H. Patel, Pierre N. Azzam 2005

机译：N200和P300的表征：与事件相关的电位的精选研究
7. Distinctive Effect of Donepezil Treatment on P300 and N200 Subcomponents of Auditory Event-Related Evoked Potentials in Alzheimer Disease Patients [O] . Arūnas Vaitkevičius, Gintaras Kaubrys, Eglė Audronytė 2015

机译：在阿尔茨米尔病患者中对多奈哌齐治疗对听觉事件相关的诱发电位的P300和N200子组件的独特作用
8. P300 Component of the Auditory Event-Related Potential: InterlaboratoryConsistency and Test-Retest Reliability [R] . Trejo, L. J., Inlow, M., Stanny, R. R., 1991

机译：p300听觉事件相关电位的组成部分：实验室间一致性和测试 - 再测试可靠性

Distinctive Effect of Donepezil Treatment on P300 and N200 Subcomponents of Auditory Event-Related Evoked Potentials in Alzheimer Disease Patients

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