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Structural and Biological Behaviour of Co(II) Cu(II) and Ni(II) Metal Complexes of Some Amino Acid Derived Schiff-Bases

机译:某些氨基酸衍生的席夫碱的Co(II)Cu(II)和Ni(II)金属配合物的结构和生物学行为

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摘要

Biologically active tridentate amino acid (Alanine, Glycine & Tyrosine) derived Schiff-bases and their Co(II), Cu(II) & Ni(II) complexes have been synthesised and characterised on the basis of their conductance and magnetic measurements, elemental analysis and 13C-NMR, 1H-NMR, IR and electronic spectral data. These Schiff-bases and their complexes have been evaluated for their antibacterial activity against bacterial species such as Staphylococcus aureus, Escherichia coli, Klebsiella pneumonae, Proteus vulgarus and Pseudomonas aeruginosa and this activity data show the metal complexes to be more antibacterial than the Schiff-bases against one or more bacterial species.
机译:合成了具有生物活性的三齿氨基酸(丙氨酸,甘氨酸和酪氨酸)希夫碱及其Co(II),Cu(II)和Ni(II)配合物,并根据其电导和磁测量,元素分析对其进行了表征。和 13 C-NMR, 1 H-NMR,IR和电子光谱数据。已评估了这些席夫碱及其复合物对诸如金黄色葡萄球菌,大肠埃希菌,肺炎克雷伯菌,寻常变形杆菌和铜绿假单胞菌等细菌物种的抗菌活性,并且该活性数据表明金属配合物比席夫碱更具抗菌性。针对一种或多种细菌。

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