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首页> 美国卫生研究院文献>Molecules >Fumigant Toxicity of Oriental Sweetgum (Liquidambar orientalis) and Valerian (Valeriana wallichii) Essential Oils and Their Components Including Their Acetylcholinesterase Inhibitory Activity against Japanese Termites (Reticulitermes speratus)
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Fumigant Toxicity of Oriental Sweetgum (Liquidambar orientalis) and Valerian (Valeriana wallichii) Essential Oils and Their Components Including Their Acetylcholinesterase Inhibitory Activity against Japanese Termites (Reticulitermes speratus)

机译：东方甜香和缬草（Valeriana wallichii）香精油及其成分对日本白蚁（Reticulitermes speratus）的熏蒸毒性包括对乙酰胆碱酯酶的抑制活性。

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This study investigated the fumigant toxicity of oriental sweetgum (Liquidambar orientalis) and valerian (Valeriana wallichii) essential oils and their components against the Japanese termite (Reticulitermes speratus). The fumigant toxicity of oriental sweetgum and valerian oil differed significantly according to exposure time. Oriental sweetgum showed toxicity at short exposure times (2 days), and the toxicity of valerian oil was high 7 days after treatment. The main constituents of oriental sweetgum and valerian oils were tested individually for their fumigant toxicity against Japanese termites. Among the test compounds, benzyl alcohol, acetophenone, 1-phenyl-1-ethanol, hydrocinnamyl alcohol, trans-cinnamyl aldehyde, trans-cinnamyl alcohol, cis-asarone, styrene, and cis-ocimene showed toxicity against Japanese termites 7 days after treatment. Hydrocinnamyl alcohol and trans-cinnamyl alcohol were found to be the major contributors to the fumigant antitermitic toxicity of oriental sweetgum oil. The acetylcholinesterase (AChE) inhibition activity of two oils and their constituents was tested to determine their mode of action. Only cis-ocimene showed strong AChE inhibition activity with an IC50 value of 0.131 mg/mL. Further studies are warranted to determine the potential of these essential oils and their constituents as fumigants for termite control.
机译：这项研究调查了东方甜香（Valentiana）和缬草（Valeriana wallichii）精油及其成分对日本白蚁（Reticulitermes speratus）的熏蒸毒性。东方香和缬草油的熏蒸毒性根据暴露时间的不同而有显着差异。东方甜胶在短时间内（2天）显示出毒性，治疗后7天缬草油的毒性很高。东方甜木和缬草油的主要成分已针对其对日本白蚁的熏蒸毒性进行了单独测试。在测试化合物中，处理后7天，苯甲醇，苯乙酮，1-苯基-1-乙醇，氢肉桂醇，反式肉桂醛，反式肉桂醇，顺式松香，苯乙烯和顺式香茅草显示出对日本白蚁的毒性。发现氢肉桂醇和反式肉桂醇是东方甜菜油熏蒸剂抗白蚁毒性的主要贡献者。测试了两种油及其成分的乙酰胆碱酯酶（AChE）抑制活性，以确定它们的作用方式。仅顺式-ocimene具有较强的AChE抑制活性，IC50值为0.131 mg / mL。有必要进行进一步的研究以确定这些精油及其成分作为熏蒸剂防治白蚁的潜力。

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