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Identification of Onosma visianii Roots Extract and Purified Shikonin Derivatives as Potential Acaricidal Agents against Tetranychus urticae

机译:鉴别小菜豆根提取物和纯化的紫草素衍生物作为潜在的杀螨剂

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摘要

There is an increasing need for the discovery of reliable and eco-friendly pesticides and natural plant-derived products may play a crucial role as source of new active compounds. In this research, a lipophilic extract of Onosma visianii roots extract containing 12% of shikonin derivatives demonstrated significant toxicity and inhibition of oviposition against Tetranychus urticae mites. Extensive chromatographic separation allowed the isolation of 11 naphthoquinone derivatives that were identified by spectral techniques and were tested against Tetranychus urticae. All the isolated compounds presented effects against the considered mite and isobutylshikonin (>1) and isovalerylshikonin (>2) were the most active, being valuable model compounds for the study of new anti-mite agents.
机译:越来越需要发现可靠和环保的农药,天然植物来源的产品作为新的活性化合物的来源可能起着至关重要的作用。在这项研究中,含有12%紫草素衍生物的小叶鬼臼根提取物的亲脂性提取物显示出显着的毒性,并抑制了对四叶螨的产卵。广泛的色谱分离可分离出11种萘醌衍生物,这些衍生物已通过光谱技术鉴定并针对荨麻疹进行了测试。所有分离出的化合物都对螨和异丁基紫草素(> 1 )和异戊基紫草素(> 2 )具有最强的活性,是研究新型抗螨药的有价值的模型化合物。螨虫。

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