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Analytical Techniques and Pharmacokinetics of Gastrodia elata Blume and Its Constituents

机译：天麻及其成分的分析技术和药代动力学

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摘要

Gastrodia elata Blume (G. elata), commonly called Tianma in Chinese, is an important and notable traditional Chinese medicine (TCM), which has been used in China as an anticonvulsant, analgesic, sedative, anti-asthma, anti-immune drug since ancient times. The aim of this review is to provide an overview of the abundant efforts of scientists in developing analytical techniques and performing pharmacokinetic studies of G. elata and its constituents, including sample pretreatment methods, analytical techniques, absorption, distribution, metabolism, excretion (ADME) and influence factors to its pharmacokinetics. Based on the reported pharmacokinetic property data of G. elata and its constituents, it is hoped that more studies will focus on the development of rapid and sensitive analytical techniques, discovering new therapeutic uses and understanding the specific in vivo mechanisms of action of G. elata and its constituents from the pharmacokinetic viewpoint in the near future. The present review discusses analytical techniques and pharmacokinetics of G. elata and its constituents reported from 1985 onwards.
机译：天麻（G. elata）（俗称天麻）是一种重要而著名的中药（TCM），自从中国以来就被用作抗惊厥药，镇痛药，镇静药，抗哮喘药，抗免疫药。远古时代。这篇综述的目的是概述科学家在开发分析技术和进行G. elata及其成分的药代动力学研究方面所做的大量努力，包括样品预处理方法，分析技术，吸收，分布，代谢，排泄（ADME）以及影响其药代动力学的因素。基于报道的G. elata及其成分的药代动力学特性数据，希望更多的研究将集中于快速和灵敏的分析技术的发展，发现新的治疗用途并了解G. elata的特定体内作用机制。从药代动力学的角度来看其组成及其组成。本综述讨论了1985年以来报道的G. elata及其成分的分析技术和药代动力学。

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