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Recent Applications of Molecularly Imprinted Sol-Gel Methodology in Sample Preparation

机译:分子印迹Sol-Gel方法在样品制备中的最新应用

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摘要

Due to their selectivity and chemical stability, molecularly imprinted polymers have attracted great interest in sample preparation. Imprinted polymers have been applied for the extraction and the enrichment of different sorts of trace analytes in biological and environmental samples before their analysis. Additionally, MIPs are utilized in various sample preparation techniques such as SPE, SPME, SBSE and MEPS. Nevertheless, molecularly imprinted polymers suffer from thermal (stable only up to 150 °C) and mechanical stability issues, improper porosity and poor capacity. The sol-gel methodology as a promising alternative to address these limitations allowing the production of sorbents with controlled porosity and higher surface area. Thus the combination of molecularly imprinted technology and sol-gel technology can create influential materials with high selectivity, high capacity and high thermal stability. This work aims to present an overview of molecularly imprinted sol-gel polymerization methods and their applications in analytical and bioanalytical fields.
机译:由于它们的选择性和化学稳定性,分子印迹聚合物在样品制备中引起了极大的兴趣。印迹聚合物已用于分析之前在生物和环境样品中提取和富集各种痕量分析物。此外,MIP还用于各种样品制备技术中,例如SPE,SPME,SBSE和MEPS。然而,分子印迹聚合物遭受热(仅在高达150°C的温度下稳定)和机械稳定性问题,不适当的孔隙率和较差的容量。溶胶-凝胶法是解决这些局限性的有前途的替代方法,可以生产出孔隙率受控且表面积较大的吸附剂。因此,分子印迹技术和溶胶-凝胶技术的结合可以产生具有高选择性,高容量和高热稳定性的有影响的材料。这项工作旨在概述分子印迹溶胶-凝胶聚合方法及其在分析和生物分析领域中的应用。

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