首页> 美国卫生研究院文献>Neuro-Oncology >P04.58 A new computational method for comprehensive estimation of anti tumor efficacy of tumor treating fields (TTFields). Accounting for field intensity exposure time and unwanted spatial field correlation.

【2h】

P04.58 A new computational method for comprehensive estimation of anti tumor efficacy of tumor treating fields (TTFields). Accounting for field intensity exposure time and unwanted spatial field correlation.

机译：P04.58一种新的计算方法用于综合评估肿瘤治疗场（TTFields）的抗肿瘤功效。考虑到场强曝光时间和不想要的空间场相关性。

代理获取

本网站仅为用户提供外文OA文献查询和代理获取服务，本网站没有原文。下单后我们将采用程序或人工为您竭诚获取高质量的原文，但由于OA文献来源多样且变更频繁，仍可能出现获取不到、文献不完整或与标题不符等情况，如果获取不到我们将提供退款服务。请知悉。

页面导航

摘要
著录项
相似文献
相关主题

摘要

BackgroundThe non-invasive glioblastoma treatment, tumor treating fields (TTFields, Optune^®), uses alternating electrical fields (200 kHz) to inhibit cancer cell division. TTFields are induced by two sequentially active pairs of transducer arrays placed on the patient’s scalp. Finite element (FE) methods are used to estimate the field intensity of TTFields. To date, calculations have focused entirely on field intensity, neglecting field angle and exposure time that also influence efficacy. Based on principal component analysis, this study derives a novel approach to quantify mean intensity of TTFields together with unwanted effects from spatial field correlation, indexed as fractional anisotropy (FA).

机译：背景技术非侵入性胶质母细胞瘤治疗是肿瘤治疗领域（TTFields，Optune ^{®），它使用交变电场（200 kHz）来抑制癌细胞分裂。 TTFields由放置在患者头皮上的两对依次活动的换能器阵列对感应产生。有限元（FE）方法用于估计TTFields的场强。迄今为止，计算完全集中在场强上，忽略了场角和曝光时间，这也会影响功效。基于主成分分析，这项研究得出了一种新颖的方法，可以量化TTFields的平均强度以及空间场相关性的不想要的影响，以分数各向异性（FA）表示。}

著录项

期刊名称 Neuro-Oncology
作者
A R Korshoej; A Thielscher;
展开▼
作者单位

展开▼
年(卷),期 2018(20),Suppl 3
年度 2018
页码 iii292–iii293
总页数 1
原文格式 PDF
正文语种
中图分类神经病学;肿瘤学;
关键词

相似文献

外文文献
专利

1. Tumor-treating fields (TTFields) induce immunogenic cell death resulting in enhanced antitumor efficacy when combined with anti-PD-1 therapy [J] . Voloshin Tali, Kaynan Noa, Davidi Shiri, Cancer immunology, immunotherapy : . 2020,第7期

机译：肿瘤治疗田地（TTFIELDS）诱导免疫原性细胞死亡，导致与抗PD-1治疗组合时的增强抗肿瘤功效
2. Immunomodulatory Effect of Tumor Treating Fields (TTFields) Results in Enhanced Antitumor Efficacy When Combined with Anti-PD-1 Therapy in Mouse Model of Lung Cancer [J] . Voloshin T., Davidi S., Porat Y., International Journal of Radiation Oncology, Biology, Physics . 2019,第1期

机译：肿瘤治疗田间（TTFIELDS）的免疫调节作用导致肺癌小鼠模型中的抗PD-1治疗时增强抗肿瘤功效
3. Immunogenic Cell Death Induced by Tumor Treating Fields (TTFields) Enhances Efficacy When Combined with Anti-PD-1 Therapy in Lung and Colon Cancer Animal Models [J] . Voloshin T., Kaynan N., Davidi S., International Journal of Radiation Oncology, Biology, Physics . 2019,第1Suppla期

机译：肿瘤治疗田间（TTFIELS）诱导的免疫原性细胞死亡增强了肺癌和结肠癌动物模型的抗PD-1治疗时的疗效
4. Estimating the Intensity and Anisotropy of Tumor Treating Fields Jsing Singular Value Decomposition. Towards a More Comprehensive Estimation of Anti-tumor Efficacy [C] . Anders R. Korshoej, Axel Thielscher Annual International Conference of the IEEE Engineering in Medicine and Biology Society . 2018

机译：用奇异值分解估计肿瘤治疗领域的强度和各向异性。寻求更全面的抗肿瘤功效评估
5. EXTH-38. A NEW COMPUTATIONAL METHOD FOR COMPREHENSIVE ESTIMATION OF ANTI TUMOR EFFICACY OF TUMOR TREATING FIELDS (TTFIELDS). ACCOUNTING FOR FIELD INTENSITY EXPOSURE TIME AND UNWANTED SPATIAL FIELD CORRELATION [O] . Anders Korshoej, Nikola Mikic, Jens Christian Sørensen, -1

机译：EXTH-38。综合评估肿瘤治疗领域（TTFIELDS）抗肿瘤功效的新计算方法。场强曝光时间和不必要的空间场相关性的计算
6. P04.58 A new computational method for comprehensive estimation of anti tumor efficacy of tumor treating fields (TTFields). Accounting for field intensity, exposure time and unwanted spatial field correlation. [O] . A R Korshoej, A Thielscher 2018

机译：P04.58一种新的肿瘤治疗域抗肿瘤疗效综合估计的新计算方法（TTFIELDS）。核对现场强度，曝光时间和不需要的空间场相关性。

P04.58 A new computational method for comprehensive estimation of anti tumor efficacy of tumor treating fields (TTFields). Accounting for field intensity exposure time and unwanted spatial field correlation.

摘要

著录项

相似文献

相关主题

期刊订阅