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TBIO-16. AUTOMATED CELL ENRICHMENT AND DIGITAL CELL SORTING USING DIELECTROPHORETIC ARRAYS FOR ISOLATION OF CIRCULATING TUMOR CELLS IN PEDIATRIC BRAIN TUMOR PATIENTS

机译：TBIO-16。利用微电子阵列自动富集和数字化细胞以隔离小儿脑肿瘤患者的循环肿瘤细胞

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INTRODUCTIONLiquid biopsy has the potential to revolutionize diagnosis and management of cancer. In brain tumors, detection of cell free tumor DNA (ctDNA) and circulating tumor cells (CTC) is challenging due to low level of the circulating material. We present a novel workflow for detection and capture of CTCs.

机译：引言液体活检具有彻底改变癌症诊断和治疗的潜力。在脑肿瘤中，由于循环物质含量低，检测无细胞肿瘤DNA（ctDNA）和循环肿瘤细胞（CTC）具有挑战性。我们提出了一种新颖的检测和捕获四氯化碳的工作流程。

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期刊名称 Neuro-Oncology
作者
Katherine Barnett; Kaicen Zhu; Guomiao Shen; Jonathan Serrano; David Harter; Jeffrey Wisoff; Amanda Yaun; Shiyang Wang; Sharon Gardner; Matija Snuderl;
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年(卷),期 2018(20),Suppl 2
年度 2018
页码 i183
总页数 1
原文格式 PDF
正文语种
中图分类神经病学;肿瘤学;
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1. Mutational analysis of primary tumors and single circulating tumor cells captured by a novel dielectrophoretic microwell array system in metastatic breast cancer, oral cancer and lung cancer patients [J] . Sawada T., Morimoto A., Akiyama Y., European journal of cancer: official journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR) . 2016,第Null期

机译：新型介电泳微孔阵列系统捕获的转移性乳腺癌，口腔癌和肺癌患者的原发肿瘤和单个循环肿瘤细胞的突变分析
2. Mutational analysis of primary tumors and single circulating tumor cells captured by a novel dielectrophoretic microwell array system in metastatic breast cancer, oral cancer and lung cancer patients [J] . Sawada T., Morimoto A., Akiyama Y., European journal of cancer: official journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR) . 2016,第Null期

机译：致乳腺癌，口腔癌和肺癌患者中新型介电泳微孔阵列系统捕获的原发性肿瘤和单循环肿瘤细胞的突变分析
3. Isolation of circulating tumor cells by immunomagnetic enrichment and fluorescence-activated cell sorting (IE/FACS) for molecular profiling [J] . MagbanuaM.J.M., ParkJ.W. Methods: A Companion to Methods in Enzymology . 2013,第2期

机译：通过免疫磁富集和荧光激活细胞分选（IE / FACS）分离循环肿瘤细胞以进行分子谱分析
4. Molecular Characterization of Circulating Tumor Cells Enriched by a Microfluidic Platform in Patients with Small-Cell Lung Cancer [C] . Robert Zeilinger International Molecular Medicine Tri-Conference. . 2019

机译：小细胞肺癌患者微流体平台富集的循环肿瘤细胞的分子表征
5. A flexible micro spring array for viable enrichment of circulating tumor cells [D] . Harouaka, Ramdane. 2014

机译：灵活的微弹簧阵列，可有效富集循环中的肿瘤细胞
6. Isolation and molecular analysis of circulating tumor cells from lung cancer patients using a microfluidic chip type cell sorter [O] . Masaru Watanabe, Hirotsugu Kenmotsu, Ryo Ko, 2018

机译：使用微流控芯片型细胞分选仪对肺癌患者循环肿瘤细胞进行分离和分子分析
7. Efficiency of whole genome amplification of single circulating tumor cells enriched by CellSearch and sorted by FACS [O] . Joost F Swennenhuis, Joke Reumers, Kim Thys, 2013

机译：通过CellSearch富集并通过FACS分选的单个循环肿瘤细胞的全基因组扩增效率

TBIO-16. AUTOMATED CELL ENRICHMENT AND DIGITAL CELL SORTING USING DIELECTROPHORETIC ARRAYS FOR ISOLATION OF CIRCULATING TUMOR CELLS IN PEDIATRIC BRAIN TUMOR PATIENTS

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