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Olanzapine approved for the acute treatment of schizophrenia or manic/mixed episodes associated with bipolar I disorder in adolescent patients

机译：奥氮平被批准用于青少年患者的精神分裂症或躁狂/躁狂发作与双相性I型障碍相关的急性治疗

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BackgroundSevere and persistent mental illnesses in children and adolescents, such as early- onset schizophrenia spectrum (EOSS) disorders and pediatric bipolar disorder (pedBP), are increasingly recognized. Few treatments have demonstrated efficacy in rigorous clinical trials. Enduring response to current medications appears limited. Recently, olanzapine was approved for the treatment of adolescents with schizophrenia or acute manic/mixed episodes in pedBP.

机译：背景技术儿童和青少年的严重和持续性精神疾病，例如早发性精神分裂症谱图（EOSS）疾病和小儿双相情感障碍（pedBP），已得到越来越多的认识。很少有疗法在严格的临床试验中显示出疗效。对当前药物的持久反应似乎有限。最近，奥氮平被批准用于治疗儿童精神分裂症或pedBP急性躁狂/混合发作的青少年。

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期刊名称 Neuropsychiatric Disease and Treatment
作者
Ann E Maloney; Linmarie Sikich;
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作者单位

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年(卷),期 2010(6),-1
年度 2010
页码 749–766
总页数 18
原文格式 PDF
正文语种
中图分类神经病学;精神病学;
关键词
early-onset schizophrenia pediatric bipolar disorder antipsychotic;

机译：早发性精神分裂症;小儿双相情感障碍;抗精神病药;

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专利

1. Olanzapine approved for the acute treatment of schizophrenia or manic/mixed episodes associated with bipolar I disorder in adolescent patients [J] . Ann E Maloney, Linmarie Sikich Neuropsychiatric Disease and Treatment . 2010,第1期

机译：奥氮平被批准用于青少年患者的精神分裂症或躁狂/躁狂发作与双相性I型障碍相关的急性治疗
2. Safety and efficacy of olanzapine monotherapy and olanzapine with a mood stabilizer in 18-week treatment of manic/mixed episodes for Japanese patients with bipolar i disorder [J] . KatagiriH., TakitaY., TohenM., Current medical research and opinion . 2012,第5期

机译：奥氮平单药和奥氮平联合情绪稳定剂在日本双相性i障碍患者躁狂/混合发作18周治疗中的安全性和有效性
3. Differential efficacy of olanzapine and lithium in preventing manic or mixed recurrence in patients with bipolar I disorder based on number of previous manic or mixed episodes. [J] . Ketter TA, Houston JP, Adams DH, The journal of clinical psychiatry . 2006,第1期

机译：基于先前的躁狂或混合发作的次数，奥氮平和锂在预防躁郁症I型躁郁症患者的躁狂或混合复发中的差异疗效。
4. Effect of Asenapine on Health-Related Quality of Life in patients with manic or mixed episodes associated with bipolar I disorder [C] . Sapin C, Corson H, Hansen K International Congress on Neurobiology, Psychopharmacology Treatment Guidance . 2012

机译：aseanapine对与双极I紊乱相关的躁狂或混合发作患者健康相关生活质量的影响
5. Automated Immunohistochemical Analysis of the Orbitofrontal Cortex in Patients with Schizophrenia, Bipolar Disorder and Major Depressive Disorder [D] . Trought, Kathleen. 2017

机译：精神分裂症，双相情感障碍和重度抑郁症患者眶额皮质的自动免疫组织化学分析
6. Atypical Antipsychotics for Acute Manic and Mixed Episodes in Children and Adolescents with Bipolar Disorder [O] . Manpreet K. Singh, Terence A. Ketter, Kiki D. Chang -1

机译：非典型抗精神病药急性躁狂和在儿童和青少年混合性发作与躁郁症
7. Olanzapine approved for the acute treatment of schizophrenia or manic/mixed episodes associated with bipolar I disorder in adolescent patients [O] . Maloney, Ann E, Sikich, Linmarie 2010

机译：奥氮平被批准用于青少年患者的精神分裂症或躁狂/躁狂发作与双相性I型障碍相关的急性治疗

Olanzapine approved for the acute treatment of schizophrenia or manic/mixed episodes associated with bipolar I disorder in adolescent patients

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