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首页> 美国卫生研究院文献>Nutrients >Quantifying Sweet Taste Liker Phenotypes: Time for Some Consistency in the Classification Criteria
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Quantifying Sweet Taste Liker Phenotypes: Time for Some Consistency in the Classification Criteria

机译：量化甜味喜欢表型：在分类标准中保持一致性的时间

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摘要

Taste hedonics is a well-documented driver of food consumption. The role of sweetness in directing ingestive behavior is largely rooted in biology. One can then intuit that individual differences in sweet-liking may constitute an indicator of variations in the susceptibility to diet-related health outcomes. Despite half a century of research on sweet-liking, the best method to identify the distinct responses to sweet taste is still debated. To help resolve this issue, liking and intensity ratings for eight sucrose solutions ranging from 0 to 1 M were collected from 148 young adults (29% men). Hierarchical cluster analysis (HCA) revealed three response patterns: a sweet-liker (SL) phenotype characterized by a rise in liking as concentration increased, an inverted U-shaped phenotype with maximum liking at 0.25 M, and a sweet-disliker (SD) phenotype characterized by a decline in liking as a function of concentration. Based on sensitivity and specificity analyses, present data suggest the clearest discrimination between phenotypes is seen with 1.0 M sucrose, where a liking rating between −15 and +15 on a −50/+50 scale reliably distinguished individuals with an inverted U-shaped response from the SLs and the SDs. If the efficacy of this approach is confirmed in other populations, the discrimination criteria identified here can serve as the basis for a standard method for classifying sweet taste liker phenotypes in adults.
机译：味觉享乐主义者是食物消费的有据可查的驱动因素。甜味在指导摄食行为中的作用很大程度上源于生物学。这样一来，人们就可以看出，喜好方面的个体差异可能构成了与饮食相关的健康结果易感性变化的指标。尽管对甜味的研究进行了半个世纪的研究，但仍存在关于确定对甜味的独特反应的最佳方法的争论。为帮助解决此问题，从148位年轻人（29％的男性）中收集了8种蔗糖溶液（从0到1 M）的喜好和强度等级。层次聚类分析（HCA）显示了三种响应模式：特征是随着浓度的增加，喜好感增加的甜味喜人（SL）表型，在0.25 M时喜好程度最大的倒U型表型和甜味厌恶者（​​SD）表型的特征是喜好随浓度的下降。根据敏感性和特异性分析，目前的数据表明，在1.0 M蔗糖下，表型之间最明显的区别是明显的，其中在-50 / + 50范围内，喜欢等级介于-15和+15之间，可以可靠地区分具有倒U型反应的个体从SL和SD。如果这种方法的有效性在其他人群中得到证实，则此处确定的判别标准可以作为对成年人的甜味类表型进行分类的标准方法的基础。

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