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首页> 美国卫生研究院文献>Oncotarget >Modified protocol for enhanced recovery after surgery is beneficial for Chinese cancer patients undergoing pancreaticoduodenectomy
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Modified protocol for enhanced recovery after surgery is beneficial for Chinese cancer patients undergoing pancreaticoduodenectomy

机译：改良的手术后恢复方案对中国接受胰十二指肠切除术的癌症患者有益

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Radical surgical resection remains the only effective treatment for advanced pancreatic cancer. Effective protocols for recovery from post-operative complications that result in high rates of morbidity and mortality are therefore essential. The enhanced recovery after surgery (ERAS) protocol is an interdisciplinary multimodal concept based on modern anesthesia and analgesia combined with other fast rehabilitation parameters. It was first applied in the field of elective colorectal surgery, and eventually extended to several surgical diseases. In this study, we investigated the feasibility and safety of implementing the ERAS protocol in patients undergoing pancreaticoduodenectomy (PD). We randomly divided 159 patients who underwent PD into two groups who were managed using either ERAS or the conventional protocol. We observed that in those treated with the ERAS protocol several post-operative recovery factors were greatly improved, and there were no complications requiring readmission. We therefore propose that ERAS can improve post-operative recovery of PD patients and shorten the waiting time to chemotherapy, which may improve the overall survival of surgically treated pancreatic cancer patients.
机译：根治性手术切除仍然是晚期胰腺癌的唯一有效治疗方法。因此，从术后并发症中恢复的有效方案至关重要，该方案可导致较高的发病率和死亡率。手术后恢复提高（ERAS）方案是一种基于现代麻醉和镇痛以及其他快速康复参数的跨学科多模式概念。它首先应用于选择性结直肠手术领域，最终扩展到几种外科疾病。在这项研究中，我们调查了在接受胰十二指肠切除术（PD）的患者中实施ERAS协议的可行性和安全性。我们将159例行PD的患者随机分为两组，分别采用ERAS或常规方案治疗。我们观察到，在使用ERAS方案治疗的患者中，一些术后恢复因素得到了极大的改善，并且没有需要再次入院的并发症。因此，我们建议ERAS可以改善PD患者的术后恢复，并缩短化疗等待时间，这可能会改善经手术治疗的胰腺癌患者的整体生存率。

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