首页> 美国卫生研究院文献>The Open Biomedical Engineering Journal >Suppl 1-M5: Nanoindentation Study of Phase-pure Highly Crystalline Hydroxyapatite Coatings Deposited by Microplasma Spraying
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Suppl 1-M5: Nanoindentation Study of Phase-pure Highly Crystalline Hydroxyapatite Coatings Deposited by Microplasma Spraying

机译:Suppl 1-M5:微等离子体喷涂沉积相纯高结晶羟基磷灰石涂层的纳米压痕研究

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摘要

The present contribution has originated from a critical biomedical engineering issue e.g., loosening of metallic prostheses fixed with poly(methylmethylacrylate) (PMMA) bone cement especially in the case of hip joint replacement which ultimately forces the patient to undergo a revision surgery. Subsequently surgeons invented a cementless fixation technology introducing a bioactive hydroxyapatite (HAp) coating to the metallic implant surface. A wide variety of different coating methods have been developed to make the HAp coating on metallic implants more reliable; of which ultimately the plasma spraying method has been commercially accepted. However, the story was not yet finished at all, as many questions were raised regarding coating adherence, stability and bio-functionality in both in vitro and in vivo environments. Moreover, it has been now realized that the conventional high power plasma spraying (i.e. conventional atmospheric plasma spraying, CAPS) coating method creates many disadvantages in terms of phase impurity; reduced porosity limiting osseointegration and residual stresses which ultimately lead to inadequate mechanical properties and delamination of the coating. Further, poor crystallinity of HAp deposited by CAPS accelerates the rate of bioresorption, which may cause poor adhesion due to quick mass loss of HAp coatings. Therefore, in the present work a very recently developed method e.g., low power microplasma spraying method was utilized to coat HAp on SS316L substrates to minimize the aforementioned problems associated with commercial CAPS HAp coatings. Surgical grade SS316L has been chosen as the substrate material because it is more cost effective than Ti6Al4V and CoCrMo alloys.
机译:当前的贡献来自于关键的生物医学工程问题,例如,松开了用聚甲基丙烯酸甲酯(PMMA)骨水泥固定的金属假体,尤其是在髋关节置换的情况下,这最终迫使患者进行翻修手术。随后,外科医生发明了一种非骨水泥固定技术,在金属植入物表面引入了生物活性羟基磷灰石(HAp)涂层。已经开发出各种不同的涂覆方法,以使金属植入物上的HAp涂层更加可靠。其中等离子体喷涂方法最终已被商业接受。然而,这个故事还没有完全结束,因为在体外和体内环境中,有关涂料附着力,稳定性和生物功能性的问题很多。而且,现在已经认识到,常规的高功率等离子喷涂(即常规的大气等离子喷涂,CAPS)涂覆方法在相杂质方面产生了许多缺点。降低的孔隙度限制了骨整合和残余应力,最终导致不充分的机械性能和涂层分层。此外,CAPS沉积的HAp结晶度差会加速生物吸收的速度,由于HAp涂层的快速质量损失,可能会导致粘附力差。因此,在本工作中,采用了一种最新开发的方法,例如低功率微等离子体喷涂方法,将HAp涂覆在SS316L基底上,以使与商业CAPS HAp涂层相关的上述问题最小化。之所以选择手术级SS316L作为基材,是因为它比Ti6Al4V和CoCrMo合金更具成本效益。

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