Intra-Arterial MSC Transplantation Restores Functional Capacity After Skeletal Muscle Trauma

机译：骨骼肌创伤后动脉内MSC移植可恢复功能

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Introduction:Skeletal muscle trauma leads to severe functional deficits, which cannot be addressed by current treatment options. Our group could show the efficacy of local transplantation of mesenchymal stroma cells (MSCs) for the treatment of injured muscles. While local application of MSCs has proven to be effective, we hypothesized that a selective intra-arterial transplantation would lead to a better distribution of the cells and so improved physiological recovery of muscle function.

机译：简介：骨骼肌创伤导致严重的功能缺陷，目前的治疗方法无法解决。我们的小组可以显示出间充质基质细胞（MSCs）局部移植治疗受伤肌肉的功效。尽管已证明局部应用MSC是有效的，但我们假设选择性动脉内移植将导致细胞更好的分布并因此改善肌肉功能的生理恢复。

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期刊名称 The Open Orthopaedics Journal
作者
Philipp von Roth; Georg N Duda; Piotr Radojewski; Bernd Preininger; Kristin Strohschein; Eric Röhner; Carsten Perka; Tobias Winkler;
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作者单位

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年(卷),期 2012(6),-1
年度 2012
页码 352–356
总页数 5
原文格式 PDF
正文语种
中图分类外科学;
关键词
Muscle trauma regeneration stem cells stroma cells intra-arterial systemic.;

机译：肌肉;创伤;再生;干细胞;基质细胞;动脉内;全身。;

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专利

1. Intra-Arterial MSC Transplantation Restores Functional Capacity After Skeletal Muscle Trauma [J] . Revision Received Date: The Open Orthopaedics Journal . 2012,第1期

机译：骨骼肌创伤后动脉内MSC移植可恢复功能
2. Intra-arterial transplantation of adult bone marrow cells restores blood flow and regenerates skeletal muscle in ischemic limbs. [J] . Liu Q, Chen Z, Terry T Vascular and endovascular surgery . 2009,第5期

机译：成年骨髓细胞的动脉内移植可恢复缺血肢体的血流并再生其骨骼肌。
3. Transplantation of adipose tissue-derived stromal cells increases mass and functional capacity of damaged skeletal muscle. [J] . Bacou F, el Andalousi RB, Daussin PA, Cell transplantation . 2004,第2期

机译：脂肪组织来源的基质细胞的移植增加了受损骨骼肌的质量和功能能力。
4. Utilizing Multifunctional Alginate Scaffolds for the Regeneration of Skeletal Muscle Defects in a Rat Crush Trauma Model [C] . Taimoor Qazi, Matthias Pumberger, Tobias Winkler, European conference on biomaterials . 2014

机译：利用多功能藻酸盐支架再生大鼠挤压伤模型的骨骼肌缺损。
5. Skeletal Muscle Satellite Cells Have a MyoD-Positive Developmental Origin and Activated MyoD-Positive Satellite Cells Maintain Their Self-renewal Capacity during Adult Muscle Regeneration. [D] . Kanisicak, Onur. 2011

机译：骨骼肌卫星细胞具有MyoD阳性发育起源，而活化的MyoD阳性卫星细胞在成年肌肉再生过程中保持其自我更新能力。
6. Impairment of early fracture healing by skeletal muscle trauma is restored by FK506 [O] . Brady J. Hurtgen, Beth E. P. Henderson, Catherine L. Ward, 2017

机译：FK506恢复了骨骼肌创伤对早期骨折愈合的损害
7. Intra-Arterial MSC Transplantation Restores Functional Capacity After Skeletal Muscle Trauma [O] . Philipp von Roth, Georg N Duda, Piotr Radojewski, 2012

机译：动脉内部MSC移植恢复骨骼肌创伤后的功能能力
8. Promotion of a Functional Fibrosis in Skeletal Muscle with Volumetric Muscle Loss Injury Following the Transplantation of Muscle-ECM. [R] . Corona, B. T., Wu, X., Ward, C. L., 2013

机译：肌肉 - ECm移植后促进骨骼肌功能性纤维化伴容量性肌肉损伤。

Intra-Arterial MSC Transplantation Restores Functional Capacity After Skeletal Muscle Trauma

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