• 主题
高级搜索  >
历史搜索 清空历史
首页> 美国卫生研究院文献>Pharmaceutical Biology >Amaranth (Amaranthus cruentus L.) and canola (Brassica napus L.) oil impact on the oxidative metabolism of neutrophils in the obese patients*
【2h】

Amaranth (Amaranthus cruentus L.) and canola (Brassica napus L.) oil impact on the oxidative metabolism of neutrophils in the obese patients*

机译：mar菜油（Amaranthus cruentus L.）和低芥酸菜籽油（Brassica napus L.）对肥胖患者中性粒细胞氧化代谢的影响*

代理获取
本网站仅为用户提供外文OA文献查询和代理获取服务，本网站没有原文。下单后我们将采用程序或人工为您竭诚获取高质量的原文，但由于OA文献来源多样且变更频繁，仍可能出现获取不到、文献不完整或与标题不符等情况，如果获取不到我们将提供退款服务。请知悉。
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

>Context: Amaranth and canola oils have been used traditionally. Amaranth has been identified as being of interest because of its outstanding nutritive value. Amaranth oil is a rich source of highly unsaturated fats and so could be a valuable dietary alternative for individuals affected with obesity. Reactive oxygen species (ROS) are postulated to be involved in systemic inflammation and oxidative stress. Activated polymorphonuclear neutrophils (PMNs) generate high amounts of reactive oxygen species.>Objective: Our study investigates the impact of amaranth and canola oils supplementation on oxidative metabolism in patients with obesity. We hypothesized that, due to its lipid-lowering and antioxidant properties, amaranth and canola oil would protect against oxidative stress.>Materials and methods: We tested 19 obese patients [body mass index (BMI) = 41.1 ± 7.8 kg/m2, (mean ± SD)]. The protocol consisted of two stages: a run-in phase of 2 weeks and an experimental stage – canola or amaranth oil supplementation (20 mL/d) with calorie restriction diet for 3 weeks. The neutrophil oxidative burst was expressed by fluorescence intensity (IF).>Results: The oxidative burst had increased significantly at the end of treatment in both groups IF: (21.4 ± 11.15 vs. 35.9 ± 20.3; mean ± SD) p < 0.05. The levels of IF were significantly higher in neutrophils of patients who received canola oil (41.05 ± 25.3) compared to those who received amaranth oil (28.4 ± 11.8) p < 0.05.>Conclusions: Canola oil exerts possible effects on oxidative burst activity in neutrophils in vivo conditions.
机译：>上下文：传统上使用A菜籽油和低芥酸菜籽油。由于菜具有突出的营养价值，因此被认为很受关注。 mar菜油是高度不饱和脂肪的丰富来源，因此对于肥胖者而言，它可能是一种有价值的饮食替代品。假定活性氧（ROS）参与全身性炎症和氧化应激。活化的多形核中性粒细胞（PMN）产生大量的活性氧。>目的：我们的研究调查了mar菜籽和低芥酸菜籽油补充剂对肥胖患者氧化代谢的影响。我们假设，由于mar菜籽油和低芥酸菜籽油具有降脂和抗氧化的作用，因此可以抵御氧化应激。>材料和方法：我们测试了19名肥胖患者[体重指数（BMI）= 41.1± 7.8 kg / m 2 ，（平均值±SD）。该方案包括两个阶段：磨合期2周和实验阶段–芥花籽油或a菜油补充剂（20μmL/ d），并限制卡路里饮食3周。中性粒细胞的氧化爆发由荧光强度（IF）表示。>结果：两组治疗结束时氧化爆发均显着增加：（21.4±11.15 vs. 35.9±20.3；平均值±± SD）p ＜0.05。接受低芥酸菜籽油治疗的中性粒细胞的IF水平（41.05±±25.3）比接受a菜油的患者（28.4±±11.8）的p）<0.05。>结论：低芥酸菜子油具有一定的作用在体内条件下对中性粒细胞氧化爆发活性的影响

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
代理获取

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号