首页> 美国卫生研究院文献>Plant Signaling Behavior >Involvement of the S4-S5 linker and the C-linker domain regions to voltage-gating in plant Shaker channels: Comparison with animal HCN and Kv channels
【2h】

Involvement of the S4-S5 linker and the C-linker domain regions to voltage-gating in plant Shaker channels: Comparison with animal HCN and Kv channels

机译:S4-S5接头和C接头结构域区域参与植物振荡器通道的电压门控:与动物HCN和Kv通道的比较

代理获取
本网站仅为用户提供外文OA文献查询和代理获取服务,本网站没有原文。下单后我们将采用程序或人工为您竭诚获取高质量的原文,但由于OA文献来源多样且变更频繁,仍可能出现获取不到、文献不完整或与标题不符等情况,如果获取不到我们将提供退款服务。请知悉。

摘要

Among the different transport systems present in plant cells, Shaker channels constitute the major pathway for K+ in the plasma membrane. Plant Shaker channels are members of the 6 transmembrane-1 pore (6TM-1P) cation channel superfamily as the animal Shaker (Kv) and HCN channels. All these channels are voltage-gated K+ channels: Kv channels are outward-rectifiers, opened at depolarized voltages and HCN channels are inward-rectifiers, opened by membrane hyperpolarization. Among plant Shaker channels, we can find outward-rectifiers, inward-rectifiers and also weak-rectifiers, with weak voltage dependence. Despite the absence of crystal structures of plant Shaker channels, functional analyses coupled to homology modeling, mostly based on Kv and HCN crystals, have permitted the identification of several regions contributing to plant Shaker channel gating. In the present mini-review, we make an update on the voltage-gating mechanism of plant Shaker channels which seem to be comparable to that proposed for HCN channels.
机译:在植物细胞中存在的不同转运系统中,摇床通道是质膜中K + 的主要途径。植物摇床通道是动物摇床(Kv)和HCN通道的6个跨膜1孔(6TM-1P)阳离子通道超家族的成员。所有这些通道都是电压门控的K + 通道:Kv通道是向外整流器,在去极化电压下打开,而HCN通道是向内整流器,通过膜超极化打开。在植物振荡器通道中,我们可以找到对电压的依赖性较弱的向外整流器,向内整流器以及弱整流器。尽管缺少植物摇床通道的晶体结构,但功能分析和同源性建模(主要基于Kv和HCN晶体)相结合,已允许鉴定有助于植物摇床通道门控的几个区域。在本次迷你审查中,我们对植物振荡器通道的电压门控机制进行了更新,该机制似乎与为HCN通道提议的相当。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
代理获取

客服邮箱:kefu@zhangqiaokeyan.com

京公网安备:11010802029741号 ICP备案号:京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有
  • 客服微信

  • 服务号