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首页> 美国卫生研究院文献>Polymers >Electro-Active Polymers (EAPs): A Promising Route to Design Bio-Organic/Bioinspired Platforms with on Demand Functionalities
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Electro-Active Polymers (EAPs): A Promising Route to Design Bio-Organic/Bioinspired Platforms with on Demand Functionalities

机译：电活性聚合物（EAP）：设计具有按需功能的生物有机/生物启发平台的有前途的途径

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Through recent discoveries and new knowledge among correlations between molecular biology and materials science, it is a growing interest to design new biomaterials able to interact—i.e., to influence, to guide or to detect—with cells and their surrounding microenvironments, in order to better control biological phenomena. In this context, electro-active polymers (EAPs) are showing great promise as biomaterials acting as an interface between electronics and biology. This is ascribable to the highly tunability of chemical/physical properties which confer them different conductive properties for various applicative uses (i.e., molecular targeting, biosensors, biocompatible scaffolds). This review article is divided into three parts: the first one is an overview on EAPs to introduce basic conductivity mechanisms and their classification. The second one is focused on the description of most common processes used to manipulate EAPs in the form of two-dimensional (2D) and three-dimensional (3D) materials. The last part addresses their use in current applications in different biomedical research areas including tissue engineering, biosensors and molecular delivery.
机译：通过最近的发现和分子生物学与材料科学之间相关性的新知识，人们越来越感兴趣的是设计能够与细胞及其周围微环境相互作用（即影响，指导或检测）的新生物材料，以便更好地进行研究。控制生物现象。在这种情况下，电活性聚合物（EAPs）有望作为生物材料充当电子学和生物学之间的界面，具有广阔的前景。这归因于化学/物理性质的高度可调谐性，其赋予它们用于各种应用用途（即，分子靶向，生物传感器，生物相容性支架）的不同导电性质。这篇综述文章分为三个部分：第一部分是EAP概述，介绍了基本的电导率机制及其分类。第二个重点是描述用于以二维（2D）和三维（3D）材料形式操纵EAP的最常见过程。最后一部分介绍了它们在不同生物医学研究领域（包括组织工程，生物传感器和分子递送）中的当前应用。

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