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Effect of Monascus-Fermented Soybean Extracts on Antioxidant and Skin Aging-Related Enzymes Inhibitory Activities

机译:红曲霉发酵大豆提取物对抗氧化和皮肤衰老相关酶抑制活性的影响

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摘要

We investigated the in vitro inhibitory activity against skin aging-related enzymes and antioxidant activity of Monascus-fermented soybean extracts (MFSEs) obtained by using different solvents. The highest Trolox equivalent (TE) antioxidant capacity (3.13±0.06 mM TE/g) and oxygen radical absorbance capacity (2.79±0.09 mM TE/g) of MFSEs were evaluated for the methanol and 80% ethanol extracts, respectively. The antioxidant capacities increased with increasing concentration (0.5~50 mg/mL). In addition, the methanol and 80% ethanol extracts showed an effective inhibition against tyrosinase, hyaluronidase, and elastase compared with those of acetone and hot water extracts (P<0.05). Results indicate that the inhibitory activities against skin aging-related enzymes and antioxidant properties provide evidence for the nutricosmetic potentials of Monascus-fermented soybeans.
机译:我们研究了使用不同溶剂获得的体外对皮肤衰老相关酶的抑制活性和红曲发酵大豆提取物(MFSE)的抗氧化活性。分别针对甲醇和80%乙醇提取物评估了MFSE的最高Trolox当量(TE)抗氧化剂能力(3.13±0.06 mM TE / g)和氧自由基吸收能力(2.79±0.09 mM TE / g)。抗氧化剂能力随浓度(0.5〜50 mg / mL)的增加而增加。此外,与丙酮和热水提取物相比,甲醇和80%乙醇提取物对酪氨酸酶,透明质酸酶和弹性蛋白酶具有有效的抑制作用(P <0.05)。结果表明,对皮肤衰老相关酶的抑制活性和抗氧化特性为红曲霉发酵大豆的营养潜力提供了证据。

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