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Genotyping of Dombrock and Lutheran blood group systems in blood donors from the southwestern region of the state of Paraná Southern Brazil

机译:巴西南部巴拉那州西南地区献血者的Dombrock和Lutheran血型系统基因分型

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摘要

BackgroundLutheran and Dombrock are two blood group systems with low immunogenic antigens; they can cause mild-to-moderate transfusion reactions. For both, immunophenotyping is not performed in the pretransfusion routine in Brazil. In addition, the distribution of their antigenic frequencies is an important marker of ethnicity. Thus, the goal of this study was to carry out the genotyping of the LU*01, LU*02, DO*01 and DO*02 alleles of the Lutheran and Dombrock blood group systems in blood donors from the southwestern region of the state of Paraná, Southern Brazil.
机译:背景路德教会和Dombrock是两个具有低免疫原性抗原的血型系统。它们会引起轻度至中度的输血反应。对于这两种情况,巴西的输血前常规都不会进行免疫表型分析。另外,其抗原频率的分布是种族的重要标志。因此,本研究的目的是在来自美国西南部地区的献血者中,对路德教会和Dombrock血型系统的LU * 01,LU * 02,DO * 01和DO * 02等位基因进行基因分型。巴西南部的巴拉那州。

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