首页> 美国卫生研究院文献>Revista Brasileira de Ortopedia >COMPARATIVE STUDY OF THE EFFECTS OF LOW-LEVEL LASER AND LOW-INTENSITY ULTRASOUND ASSOCIATED WITH BIOSILICATE® ON THE PROCESS OF BONE REPAIR IN THE RAT TIBIA
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COMPARATIVE STUDY OF THE EFFECTS OF LOW-LEVEL LASER AND LOW-INTENSITY ULTRASOUND ASSOCIATED WITH BIOSILICATE® ON THE PROCESS OF BONE REPAIR IN THE RAT TIBIA

机译:低水平激光和低强度超声与BIOSILICATE®结合对大鼠胫骨修复过程影响的比较研究

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摘要

Objective: Verify the effects of the association between Biosilicate® and ultrasound and, Biosilicate® and laser in bone consolidation process of rats, through the biomechanical and histological analysis. Methods: Forthy male rats were used. The animals were randomized into four groups (n=10): control group fracture no treated (CGF); group treated with Biosilicate® (BG); group treated with Biosilicate® and laser (BLG); group treated with Biosilicate® and ultrasound (BUG). Results: The biomechanical analysis showed no significant difference among any groups after 14 days post-surgery. In the morphometric analysis, the control group showed moderate presence of new formed bone tissue inside the defects areas and the Biosilicate® group showed similar results. Despite those facts, the biomaterial osteogenic potential was demonstrated by the great amount of cells and bone tissue around the particles. Curiously, the Biosilicate® plus laser or ultrasound groups showed lower amounts of bone tissue deposition when compared with control fracture and Biosilicate® groups. Conclusion: The data from this study can conclude that Biosilicate® was able to accelerate and optimized the bone consolidation, through the modulation of the inflammatory process and the stimulation of new bone formation. However, when resources were associated, there are no positive results.
机译:目的:通过生物力学和组织学分析,验证Bioethane®和超声之间的联系以及Biosil®和激光之间的联系对大鼠骨骼固结过程的影响。方法:使用雄性大鼠。将动物随机分为四组(n = 10):对照组未治疗的骨折(CGF);用Bioethane®(BG)处理的组;用Bioicide®和激光(BLG)处理的组;小组接受Bioethane®和超声(BUG)治疗。结果:术后14天,任何组之间的生物力学分析均无显着差异。在形态分析中,对照组显示在缺陷区域内适度存在新形成的骨组织,而Biosilane®组显示了相似的结果。尽管有这些事实,但颗粒周围的大量细胞和骨组织证明了生物材料具有成骨作用。奇怪的是,与对照骨折组和生物硅酸盐组相比,加上激光或超声的生物硅酸盐组显示出较少的骨组织沉积。结论:这项研究的数据可以得出结论,通过调节炎症过程和刺激新的骨骼形成,Bioicide®能够加速和优化骨骼固结。但是,当资源关联在一起时,没有积极的结果。

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