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首页> 美国卫生研究院文献>SAHARA J : Journal of Social Aspects of HIV/AIDS Research Alliance >Disability and health outcomes – from a cohort of people on long-term anti-retroviral therapy
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Disability and health outcomes – from a cohort of people on long-term anti-retroviral therapy

机译：残疾和健康状况–一群接受长期抗逆转录病毒治疗的人

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Human-immunodeficiency virus (HIV)/Acquired immunodeficiency Syndrome (AIDS) remains a major health problem in South Africa – even after two decades since the introduction of antiretroviral therapy (ART). Long-term survival with HIV is associated with new health-related issues and a risk of functional limitation/disability. The aim of this study was to assess functional limitation associated with HIV/AIDS among people living with HIV (PLHIV) in South Africa. This study is a cross-sectional survey using a cohort in an urban area in Gauteng province, South Africa. Data were collected using questionnaires through an interview process. The information collected included aspects such as demographics, livelihood, the state of mental and physical health, adherence and disability. A total of 1044 participants with an average age of 42 ± 12 years were included in the study, with 51.9% of the participants reporting functional limitations (WHODAS ≥ 2). These were reported mainly in the domains of participation (40.2%) and mobility (38.7%). In addition, adherence to ART, symptoms of poor physical health and depression were strongly associated with their functional limitations/disability. HIV as a chronic disease is associated with functional limitations that are not adequately addressed and pose a risk of long-term disability and negative adherence outcomes. Therefore, wellness for PLHIV/AIDS needs to include interventions that can prevent and manage disability.
机译：人类免疫缺陷病毒（HIV）/获得性免疫缺陷综合症（AIDS）仍然是南非的主要健康问题，即使在引入抗逆转录病毒疗法（ART）二十年之后。艾滋病毒的长期生存与新的健康相关问题以及功能受限/残疾的风险有关。这项研究的目的是评估南非HIV感染者（PLHIV）与HIV / AIDS相关的功能限制。这项研究是在南非豪登省的一个城市地区进行的队列调查。通过访谈过程使用问卷收集数据。收集的信息包括人口统计，生计，心理和身体健康状况，依从性和残疾等方面。研究共纳入1044名参与者，平均年龄为42±12岁，其中51.9％的参与者报告功能受限（WHODAS≥2）。这些主要报告在参与（40.2％）和流动性（38.7％）领域。此外，坚持抗逆转录病毒疗法，身体健康状况不佳和抑郁的症状与其功能限制/残疾密切相关。艾滋病毒作为一种慢性疾病，其功能限制不能得到充分解决，并可能导致长期残疾和负面依从结果。因此，艾滋病毒/艾滋病的保健需要包括可以预防和管理残疾的干预措施。

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