• 主题
高级搜索  >
历史搜索 清空历史
首页> 美国卫生研究院文献>The Scientific World Journal >Surgical Treatment of Sporadic Pancreatic Neuroendocrine Tumors: A State of the Art Review
【2h】

Surgical Treatment of Sporadic Pancreatic Neuroendocrine Tumors: A State of the Art Review

机译：散发性胰腺神经内分泌肿瘤的外科治疗：最新技术进展

代理获取
本网站仅为用户提供外文OA文献查询和代理获取服务，本网站没有原文。下单后我们将采用程序或人工为您竭诚获取高质量的原文，但由于OA文献来源多样且变更频繁，仍可能出现获取不到、文献不完整或与标题不符等情况，如果获取不到我们将提供退款服务。请知悉。
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Pancreatic neuroendocrine tumors (PNETs) are rare neoplasms. They are clinically diverse and divided into functioning and nonfunctioning disease, depending on their ability to produce symptoms due to hormone production. Surgical resection is the only curative treatment and remains the cornerstone therapy for this patient group, even in patients with advanced disease. Over the last decade there has been a noticeable trend towards more aggressive surgery as well as more minimally invasive surgery in patients with PNETs. This has resulted in improved long-term survival in patients with locally advanced and metastatic disease treated aggressively, as well as shorter hospital stays and comparable long-term outcomes in patients with limited disease treated minimally invasively. There are still controversies related to issues of surgical treatment of PNETs, such as to what extent enucleation, lymph node sampling, and vascular reconstruction are beneficial for the oncologic outcome. Histopathologic tumor classification is of high clinical importance for treatment planning and prognostic evaluation of patients with PNETs. A constant challenge, which relates to the treatment of PNETs, is the lack of an internationally accepted histopathological classification system. This paper reviews current issues on the surgical treatment of sporadic PNETs with specific focus on surgical approaches and tumor classification.
机译：胰腺神经内分泌肿瘤（PNET）是罕见的肿瘤。它们在临床上是多种多样的，根据其因激素产生而产生症状的能力，分为功能性和非功能性疾病。手术切除是唯一的治疗方法，即使对于晚期患者，手术切除仍是该患者组的基础疗法。在过去的十年中，在PNETs患者中出现了更加积极的手术以及更微创的手术的显着趋势。积极治疗的局部晚期和转移性疾病患者的长期生存期得到改善，住院时间短，微创治疗的疾病有限的患者的长期结局可比。关于PNET的外科治疗问题，仍然存在争议，例如摘除，淋巴结取样和血管重建在多大程度上有利于肿瘤治疗。组织病理学肿瘤分类对PNETs患者的治疗计划和预后评估具有重要的临床意义。与PNET的治疗有关的一个长期挑战是缺乏国际公认的组织病理学分类系统。本文回顾了散发性PNETs外科治疗的当前问题，特别关注手术方法和肿瘤分类。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
代理获取

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号