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Spectroscopic Terahertz Imaging at Room Temperature Employing Microbolometer Terahertz Sensors and Its Application to the Study of Carcinoma Tissues

机译:微测辐射热计太赫兹传感器在室温下的光谱太赫兹成像及其在癌组织研究中的应用

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摘要

A terahertz (THz) imaging system based on narrow band microbolometer sensors (NBMS) and a novel diffractive lens was developed for spectroscopic microscopy applications. The frequency response characteristics of the THz antenna-coupled NBMS were determined employing Fourier transform spectroscopy. The NBMS was found to be a very sensitive frequency selective sensor which was used to develop a compact all-electronic system for multispectral THz measurements. This system was successfully applied for principal components analysis of optically opaque packed samples. A thin diffractive lens with a numerical aperture of 0.62 was proposed for the reduction of system dimensions. The THz imaging system enhanced with novel optics was used to image for the first time non-neoplastic and neoplastic human colon tissues with close to wavelength-limited spatial resolution at 584 GHz frequency. The results demonstrated the new potential of compact RT THz imaging systems in the fields of spectroscopic analysis of materials and medical diagnostics.
机译:开发了一种基于窄带微辐射热计传感器(NBMS)和新型衍射透镜的太赫兹(THz)成像系统,用于光谱显微镜应用。使用傅里叶变换光谱法确定了太赫兹天线耦合NBMS的频率响应特性。 NBMS被发现是一种非常灵敏的频率选择性传感器,用于开发紧凑的全电子系统以进行多光谱THz测量。该系统已成功应用于不透光包装样品的主成分分析。为了减小系统尺寸,提出了一种数值孔径为0.62的薄衍射透镜。使用新型光学器件增强的太赫兹成像系统首次在584 GHz频率下成像具有接近波长限制的空间分辨率的非赘生性和赘生性人类结肠组织。结果证明了紧凑型RT THz成像系统在材料光谱分析和医学诊断领域的新潜力。

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