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Dysfunction of Cognition Patterns Measured by MATRICS Consensus Cognitive Battery (MCCB) among First Episode Schizophrenia Patients and Their Biological Parents

机译:第一阶段精神分裂症患者及其生物学父母的MATRICS共识认知电池(MCCB)测量的认知模式功能障碍

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摘要

BackgroundSchizophrenia is characterized by abnormal perception, thinking, emotions, and behaviors. Cognitive dysfunction is acknowledged as one of the most pivotal symptoms in schizophrenia. In addition to positive or negative symptoms, which had been proposed by Gallhofer in the early 1970s, schizophrenia patients suffered from cognitive impairments as well. Many studies show that there is genetic susceptibility in the first grading kinship of patients with schizophrenia. Patients with schizophrenia have cognitive impairment not only in the acute phase but also in the stable phase. Studies also show that the healthy first-grading relatives of patients with schizophrenia suffer from cognitive defects. However, there is still a lack of studies about the cognitive features of biological parents of those with schizophrenia. In this study, we speculate the biological parents of schizophrenia patients have specific cognitive dysfunction. And we explore the patterns of cognition among both schizophrenia patients and their biological parents using the Chinese version of MATRICS Consensus Cognitive Battery (MCCB).
机译:背景精神分裂症的特征在于异常的知觉,思维,情感和行为。认知功能障碍被认为是精神分裂症中最关键的症状之一。除了1970年代初期Gallhofer提出的阳性或阴性症状外,精神分裂症患者还患有认知障碍。许多研究表明,精神分裂症患者的一等亲属有遗传易感性。精神分裂症患者不仅在急性期而且在稳定期都有认知障碍。研究还表明,精神分裂症患者的健康一级亲属患有认知缺陷。但是,关于精神分裂症患者的亲生父母的认知特征仍然缺乏研究。在这项研究中,我们推测精神分裂症患者的生物学父母具有特定的认知功能障碍。我们使用中文版的《 MATRICS共识认知电池》(MCCB)探索了精神分裂症患者及其亲生父母之间的认知模式。

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