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A Nutritional Approach to the Prevention of Cancer: from Assessment to Personalized Intervention

机译:一种预防癌症的营养方法:从评估到个性化干预

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摘要

Among lifestyle factors, nutrition is one of the most important determinants of health, and represents a pivotal element of cancer risk. Nonetheless, epidemiological evidences of the relationship between several cancers and specific foods and nutrients is still inadequate, and solid conclusions are missing.Indeed, caloric restriction without malnutrition is associated to cancer prevention. Food may be also the primary route of exposure to contaminants such as metals, persistent organic pollutants, and pesticides. Exposuredisease associations and the interplay with genetic susceptibility requires further studies on genetic variation, environment, lifestyle, and chronic disease in order to eliminate and reduce associated health risks, thus contributing to improve health outcomes for the population.A primary nutritional approach for Active and Healthy Ageing (AHA) has been developed by the Nutrition group of the European Innovation Partnership (EIP) on AHA. The working group on lifestyles of the Italian Ministry of Health has developed a comprehensive approach to adequate nutrition using a consensus methodology to collect and integrate the available evidences from the literature and from the Italian experiences at the regional level, to raise the interest of other experts and relevant stakeholders to outline and scale-up joint strategies for a primary nutritional approach to cancer prevention.
机译:在生活方式因素中,营养是健康的最重要决定因素之一,并且是癌症风险的关键因素。但是,流行病学证据仍不足以说明几种癌症与特定食物和营养素之间的关系,并且缺乏确凿的结论。实际上,无营养不良的热量限制与癌症的预防有关。食物也可能是接触金属,持久性有机污染物和农药等污染物的主要途径。暴露风险关联和与遗传易感性的相互作用需要进一步研究遗传变异,环境,生活方式和慢性病,以消除和减少相关的健康风险,从而有助于改善人群的健康状况。积极健康的主要营养方法欧洲创新合作伙伴(EIP)的营养小组针对AHA开发了衰老(AHA)。意大利卫生部生活方式工作组采用一种共识方法,开发了一种全面的方法来获取充足的营养,以收集和整合来自文献和区域一级意大利经验的现有证据,以引起其他专家的兴趣。和相关利益相关者概述和扩大联合策略,以预防癌症的主要营养方法。

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