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The Rise of Imported Dengue Infections in Victoria Australia 2010–2016

机译:2010–2016年澳大利亚维多利亚州的进口登革热感染的上升

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摘要

Dengue notifications have increased dramatically over the past seven years in Victoria, Australia—a trend which has been seen nationally and reflects increased cases internationally. We reviewed the epidemiology of dengue among Victorian travellers, changes in diagnostic methods and describe the burden placed on local health systems resulting from this disease of public health importance. Cases of dengue notified to the Department of Health and Human Services in Victoria, Australia, between 1 January 2010 and 31 December 2016 were included in this review. Demographic, clinical, diagnostic methods, and risk factor data were examined using descriptive epidemiological analyses. Cases of dengue increased on average by 22% per year, with a total of 2187 cases (5.5 cases/100,000 population) notified over the 7-year reporting period. The most frequently reported country of acquisition was Indonesia (45%) followed by Thailand (14%). The use of multiple diagnostic methods, including the non-structural protein 1 antigen (NS1Ag) detection test, increased over time. The median time between onset of illness and diagnosis diminished from 9 days (IQR: 2–15) in 2010 to 4 days (IQR: 2–7) in 2016. Proportionally more cases were discharged directly from emergency departments in recent years (10% in 2010 to 28% in 2016, p < 0.001).The increasing incidence of dengue in Australia is reflective of its growing prominence as a travel medicine problem in western countries. For travellers with non-severe dengue, the improved timeliness of dengue diagnostics allows for consideration of best practice ambulatory management approaches as used in endemic areas.
机译:在过去的七年中,澳大利亚维多利亚州的登革热疫情通报急剧增加,这一趋势在全国范围内已得到体现,并反映了国际上病例的增加。我们回顾了维多利亚州旅行者中的登革热流行病学,诊断方法的变化,并描述了由这种具有公共卫生重要性的疾病导致的当地卫生系统负担。该评价包括2010年1月1日至2016年12月31日期间通知澳大利亚维多利亚州卫生与公共服务部的登革热病例。使用描述性流行病学分析检查了人口统计学,临床,诊断方法和危险因素数据。在7年的报告期内,登革热病例平均每年增加22%,共报告2187例(5.5例/ 100,000人口)。报告最频繁的收购国是印度尼西亚(45%),其次是泰国(14%)。随着时间的推移,包括非结构蛋白1抗原(NS1Ag)检测试验在内的多种诊断方法的使用在增加。从发病到诊断的平均时间从2010年的9天(IQR:2-15)减少到2016年的4天(IQR:2-7)。近年来,直接从急诊科出院的病例比例有所增加(10%在2010年达到了2016年的28%,p <0.001)。澳大利亚登革热发病率的增加反映出其作为西方国家旅行医学问题的重要性日益增加。对于没有严重登革热的旅行者,登革热诊断的及时性得到改善,可以考虑在流行地区使用最佳实践的门诊管理方法。

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