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Case-Control Study of Risk Factors Associated with Feline and Canine Chronic Kidney Disease

机译:猫和犬慢性肾脏病相关危险因素的病例对照研究

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摘要

An age-matched case-control study was initiated to determine the major risk factors associated with CKD in cats and dogs and to determine what clinical signs cat and dog owners observed before their veterinarian diagnosed their pet with CKD. When compared to controls, the feline cases were more likely to have had polydipsia and polyuria in the year before the owners' cats were diagnosed with CKD. In the dogs, increased water intake, increased urination, small size and a recent history of weight loss and bad breath were noticed by the dog owners before veterinary CKD diagnosis. Dog owners recognized abnormal drinking and urination behavior over half a year before their pet's veterinary diagnosis with CKD, and they recognized weight loss almost 4 months before CKD diagnosis. Bad breath was noticed 1.2 years before recognition of CKD by a veterinarian. Given that earlier CKD diagnosis should have been possible in most cases, clinical trials should proceed to measure the efficacy of early interventions.
机译:开始进行年龄匹配的病例对照研究,以确定猫和狗中与CKD相关的主要危险因素,并确定猫和狗所有者在兽医诊断其宠物患有CKD之前观察到的临床体征。与对照组相比,猫属病例在主人猫被诊断出患有CKD之前的一年中更容易出现多饮和多尿。在狗中,在接受兽医CKD诊断之前,发现狗的饮水量增加,排尿增加,体型较小以及最近出现体重减轻和口臭的病史。狗的主人在对宠物进行CKD的兽医诊断之前半年就认识到异常的饮酒和排尿行为,并且在CKD诊断的近四个月前就认识到体重减轻。在兽医确认CKD之前1.2年,发现口臭。鉴于在大多数情况下应该可以早期进行CKD诊断,因此应进行临床试验以评估早期干预的有效性。

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