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首页> 美国卫生研究院文献>World Journal of Gastroenterology >Pancreatic fistula after pancreatectomy: Evolving definitions preventive strategies and modern management
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Pancreatic fistula after pancreatectomy: Evolving definitions preventive strategies and modern management

机译：胰腺切除术后的胰瘘：不断发展的定义预防策略和现代管理

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Pancreatic resection is the treatment of choice for pancreatic malignancy and certain benign pancreatic disorders. However, pancreatic resection is technically a demanding procedure and whereas mortality after a pancreaticoduodenectomy is currently < 3%-5% in experienced high-volume centers, post-operative morbidity is considerable, about 30%-50%. At present, the single most significant cause of morbidity and mortality after pancreatectomy is the development of pancreatic leakage and fistula (PF). The occurrence of a PF increases the length of hospital stay and the cost of treatment, requires additional investigations and procedures, and can result in life-threatening complications. There is no universally accepted definition of PF that would allow standardized reporting and proper comparison of outcomes between different centers. However, early recognition of a PF and prompt institution of appropriate treatment is critical to the prevention of potentially devastating consequences. The present article, reviews the evolution of post resection pancreatic fistula as a concept, and discusses evolving definitions, the current preventive strategies and the management of this problem.
机译：胰腺切除术是治疗胰腺恶性肿瘤和某些良性胰腺疾病的一种选择。然而，胰腺切除术在技术上是一个苛刻的过程，尽管在经验丰富的高容量中心，胰十二指肠切除术后的死亡率目前<3％-5％，但术后发病率却很高，约为30％-50％。目前，胰腺切除术后发病和死亡的最重要的原因是胰腺漏气和瘘管（PF）的发展。 PF的出现增加了住院时间和治疗费用，需要额外的检查和程序，并可能导致危及生命的并发症。没有普遍接受的PF定义，该定义允许标准化报告和不同中心之间结果的适当比较。但是，尽早发现PF并及时采取适当的治疗对预防潜在的破坏性后果至关重要。本文从概念上回顾了切除胰腺胰瘘的演变，并讨论了不断发展的定义，当前的预防策略以及对该问题的处理。

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