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首页> 美国卫生研究院文献>World Journal of Gastroenterology >Screening test for anti-Helicobacter pylori activity of traditional Chinese herbal medicines
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Screening test for anti-Helicobacter pylori activity of traditional Chinese herbal medicines

机译：中草药抗幽门螺杆菌活性的筛选试验

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AIM: To evaluate the anti-Helicobacter pylori (H. pylori) activity of 50 traditional Chinese herbal medicines in order to provide the primary evidence for their use in clinical practice.METHODS: A susceptibility test of water extract from 50 selected traditional Chinese herbal medicines for in vitro H. pylori Sydney strain 1 was performed with broth dilution method. Anti-H. pylori activity of the selected Chinese herbal medicines was evaluated according to their minimum inhibitory concentration (MIC).RESULTS: The water extract from Rhizoma Coptidis, Radix Scutellariae and Radix isatidis could significantly inhibit the H. pylori activity with their MIC less than 7.8 mg/mL, suggesting that traditional Chinese herbal medicines have anti-inflammatory and antibacterial effects and can thus be used in treatment of H. pylori infection.CONCLUSION: Rhizoma Coptidis, Radix Scutellariae and Radix isatidis are the potential sources for the synthesis of new drugs against H. pylori.
机译：目的：评价50种中草药的抗幽门螺杆菌（H. pylori）活性，以便为它们在临床中的应用提供主要证据。方法：对50种精选中草药的水提取物进行药敏试验用肉汤稀释法进行体外幽门螺杆菌悉尼菌株1的制备。反H。结果：从黄连，黄cut和板蓝根中提取的水提取物可以显着抑制幽门螺杆菌的活性，其MIC小于7.8 mg /。毫升，表明中草药具有抗炎和抗菌作用，因此可用于治疗幽门螺杆菌感染。结论：黄连，黄cut和板蓝根是合成抗H新药的潜在来源幽门螺杆菌

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